Results 111 to 120 of about 3,652,623 (306)

Indirect likelihood inference [PDF]

open access: yes
Given a sample from a fully specified parametric model, let Zn be a given finite-dimensional statistic - for example, an initial estimator or a set of sample moments. We propose to (re-)estimate the parameters of the model by maximizing the likelihood of
Michael Creel, Dennis Kristensen
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Estimating Functions and Equations: An Essay on Historical Developments with Applications to Econometrics [PDF]

open access: yes
The idea of using estimating functions goes a long way back, at least to Karl Pearson's introduction to the method of moments in 1894. It is now a very active area of research in the statistics literature. One aim of this chapter is to provide an account
Anil K Bera   +2 more
core  

On empirical likelihood statistical functions

open access: yes
We consider the empirical likelihood method for estimation of distribution and quantile functions where side information is incorporated through moment conditions.
Yuan, Ao, Xu, Jinfeng, Zheng, Gang
core   +3 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Nonparametric estimation of mean and dispersion functions in extended generalized linear models. [PDF]

open access: yes
In this paper the interest is in regression analysis for data that show possibly overdispersion or underdispersion. The starting point for modeling are generalized linear models in which we no longer admit a linear form for the mean regression function ...
Prosdocimi, Ilaria   +2 more
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The Non-Gaussian Weak-Lensing Likelihood: A Multivariate Copula Construction and Impact on Cosmological Constraints

open access: yesThe Open Journal of Astrophysics
We present a framework to compute non-Gaussian likelihoods for two-point correlation functions. The non-Gaussianity is most pronounced on large scales that will be well-measured by stage-IV weak-lensing surveys. We show how such a multivariate likelihood
Veronika Oehl, Tilman Tröster
doaj   +1 more source

Recidivism and Likelihood Functions [PDF]

open access: yesEvaluation Quarterly, 1979
Michael D. Maltz   +2 more
openaire   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

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