Results 91 to 100 of about 3,652,623 (306)

Statistical inference of unified hybrid censoring scheme for generalized inverted exponential distribution with application to COVID-19 data

open access: yesAIP Advances
Using a unified hybrid censoring scheme, this study explores statistical inferences for products with lifetimes following the generalized inverted exponential distribution. The model’s parameters are estimated using the maximum likelihood approach.
Mustafa M. Hasaballah   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

MLEP: an R package for exploring the maximum likelihood estimates of penetrance parameters

open access: yesBMC Research Notes, 2012
Background Linkage analysis is a useful tool for detecting genetic variants that regulate a trait of interest, especially genes associated with a given disease.
Sugaya Yuki
doaj   +1 more source

Likelihood Ratio Tests for Monotone Functions

open access: yesThe Annals of Statistics, 2001
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Banerjee, Moulinath, Wellner, Jon A.
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Changes Detection in Two Images Using Walsh Functions and the Likelihood Test Method

open access: yesEngineering Transactions, 1991
The gray-value function in a local window is approximated by a series of the Walsh functions. Several terms of this series adequately model the gray-value function in the window, and the remaining variability can be attributed to noise.
M. Nieniewski, P.K. Pathak
doaj  

Efficient Likelihood Evaluation of State-Space Representations [PDF]

open access: yes
We develop a numerical procedure that facilitates efficient likelihood evaluation in applications involving non-linear and non-Gaussian state-space models.
David N. DeJong   +4 more
core  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

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