Results 101 to 110 of about 1,540,370 (339)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Changes Detection in Two Images Using Walsh Functions and the Likelihood Test Method

open access: yesEngineering Transactions, 1991
The gray-value function in a local window is approximated by a series of the Walsh functions. Several terms of this series adequately model the gray-value function in the window, and the remaining variability can be attributed to noise.
M. Nieniewski, P.K. Pathak
doaj  

melt: Multiple Empirical Likelihood Tests in R

open access: yesJournal of Statistical Software
Empirical likelihood enables a nonparametric, likelihood-driven style of inference without relying on assumptions frequently made in parametric models.
Eunseop Kim   +2 more
doaj   +1 more source

New RooFit PyROOT interfaces for connections with Machine Learning [PDF]

open access: yesEPJ Web of Conferences
With the growing datasets of HE(N)P experiments, statistical analysis becomes more computationally demanding, requiring improvements in existing statistical analysis algorithms and software.
Rembser Jonas   +2 more
doaj   +1 more source

Non-Gaussian Likelihood Function

open access: yes, 1995
We generalize the maximum likelihood method to non-Gaussian distribution functions by means of the multivariate Edgeworth expansion. We stress the potential interest of this technique in all those cosmological problems in which the determination of a non-Gaussian signature is relevant, e.g.
openaire   +2 more sources

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

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