In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Use of diagnostic likelihood ratio of outcome to evaluate misclassification bias in the planning of database studies. [PDF]
BMC Med Inform Decis Mak, 2022 Ii Y, Hiro S, Nakazuru Y.
europepmc +1 more source
Adjusted empirical likelihood estimation of the youden index and associated threshold for the bigamia model [PDF]
The Youden index is a widely used measure in the framework of medical diagnostic, where the effectiveness of a biomarker (screening marker or predictor) for classifying a disease status is studied.
Emilio Leton, Elisa M. Molanes
core
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Application of empirical likelihood ratio test in AR(1) time series model for PM<sub>2.5</sub> forecasting in Guwahati city of Assam. [PDF]
Sci RepSerrao V, Poojari S, B I, Rao KA.
europepmc +1 more source
FEBS Open Bio, EarlyView.The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley +1 more source
Signed log-likelihood ratio test for the scale parameter of Poisson Inverse Weibull distribution with the development of PIW4LIFETIME web application. [PDF]
PLoS OneYodnual S, Chumnaul J.
europepmc +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Effects of prescreening for likelihood ratio approaches in the forensic identification of source problems. [PDF]
Forensic Sci Int SynergBorchert D +4 more
europepmc +1 more source
Likelihood ratio test for genetic association study with case-control data under Probit model. [PDF]
J Appl Stat, 2022 Sheng Z, Liu Y, Li P, Qin J.
europepmc +1 more source