Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Likelihood Ratio Test and the Evidential Approach for 2 × 2 Tables. [PDF]
Cahusac PMB.
europepmc +1 more source
Likelihood ratio test for genetic association study with case-control data under Probit model. [PDF]
Sheng Z, Liu Y, Li P, Qin J.
europepmc +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
A method for determining potential parental contamination: linkage disequilibrium-based log-likelihood ratio analysis for IVF-PGT. [PDF]
Bo L +11 more
europepmc +1 more source
Likelihood ratio statistics for gene set enrichment in Alzheimer's disease pathways. [PDF]
Bryan J +10 more
europepmc +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Likelihood ratio combination of multiple biomarkers via smoothing spline estimated densities. [PDF]
Du Z, Du P, Liu A.
europepmc +1 more source
Small RNA pathways in mammalian oocytes
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Empirical Likelihood based on Hypothesis Testing
AMS classifications: 62G10; 62G20; 62G30;estimation;testing ...
Einmahl, J.H.J., McKeague, I.W.
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