Results 91 to 100 of about 101,218 (287)

"Empirical Likelihood-Based Inference in Conditional Moment Restriction Models" [PDF]

This paper proposes an asymptotically efficient method for estimating models with conditional moment restrictions. Our estimator generalizes the maximum empirical likelihood estimator (MELE) of Qin and Lawless (1994).
Hyungtaik Ahn, Yuichi Kitamura, Gautam Tripathi   +2 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Bootstrap Confidence Regions Using the Likelihood Ratio Statistic in Mixture Models [PDF]

, 1991
27 pages, 1 article*Bootstrap Confidence Regions Using the Likelihood Ratio Statistic in Mixture Models* (Feng, Ziding; McCulloch, Charles E.) 27 ...
Feng, Ziding, Cornell University. Dept. of Biological Statistics and Computational Biology., McCulloch, Charles E., Cornell University. Biometrics Unit., Cornell University. Dept. of Biometrics.   +4 more
core  

Log-likelihood-ratio statistic D = 2(L_w − L_g), for 156 villages where L_w and L_g denote maximised log-likelihoods for Weibull and Gamma fits, respectively.

, 2016
Log-likelihood-ratio statistic D = 2(Lw − Lg), for 156 villages where Lw and Lg denote maximised log-likelihoods for Weibull and Gamma fits, respectively.
Tony Ukety (739332), Peter J Diggle (2923260), Alison P Galvani (11466), Innocent Takougang (3372524), Samuel Wanji (216392), Daniela K Schlüter (3372527), Martial L Ndeffo-Mbah (3372521)   +6 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Empirical likelihood estimators for the error distribution in nonparametric regression models [PDF]

The aim of this paper is to show that existing estimators for the error distribution in nonparametric regression models can be improved when additional information about the distribution is included by the empirical likelihood method.
Kiwitt, Sebastian, Neumeyer, Natalie, Nagel, Eva-Renate   +2 more
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

The likelihood ratio test for homogeneity in bivariate normal mixtures

, 2006
This paper investigates the asymptotic properties of the likelihood ratio statistic for testing homogeneity in a bivariate normal mixture model with known covariance.
Smith, Bruce, Song Qin, Yong
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Adjusted empirical likelihood confidence regions for stationary autoregressive models

四川大学学报. 自然科学版
Autoregressive models are widely used in diverse fields such as economics and information science.The statistical inference problem of autoregressive models is an important research topic in statistics.This paper aims at the adjusted empirical likelihood
HOU Meng-Zhe, QIN Yong-Song, ZHANG Zheng-Jia   +2 more
doaj