Results 91 to 100 of about 3,536,755 (285)

Echo Cancellation : the generalized likelihood ratio test for double-talk vs. channel change [PDF]

, 2009
Echo cancellers are required in both electrical (impedance mismatch) and acoustic (speaker-microphone coupling) applications. One of the main design problems is the control logic for adaptation.
Bermudez, José Carlos Moreira, Tourneret, Jean-Yves, Bershad, Neil J.   +2 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

The Bayesian Score Statistic [PDF]

We propose a novel Bayesian test under a (noninformative) Jeffreys’ prior speciï¬ca- tion. We check whether the ï¬xed scalar value of the so-called Bayesian Score Statistic (BSS) under the null hypothesis is a plausible realization from its known and ...
Kleijn, R.H., Kleibergen, F.R., Paap, R.
core   +2 more sources

Empirical Likelihood Statistical Inference for the BINAR(1) Process

Mathematics
In this paper, we apply the empirical likelihood (EL) approach to the bivariate first-order integer-valued autoregressive (BINAR(1)) model. The maximum empirical likelihood (MEL) estimator for this process is constructed by the empirical likelihood ratio
Yan Liu, Yifei Wang, Bo Shao
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Likelihood Ratio Tests for Multiply Imputed Datasets: Introducing milrtest [PDF]

Through the use of user-written programs, primarily mim (Carlin, Galati, and Royston, 2008), Stata users can analyze multiply imputed (MI) datasets. Among other capabilities, mim allows the user to estimate a range of regression models and to perform a ...
Rose Medeiros
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

"Empirical Likelihood-Based Inference in Conditional Moment Restriction Models" [PDF]

This paper proposes an asymptotically efficient method for estimating models with conditional moment restrictions. Our estimator generalizes the maximum empirical likelihood estimator (MELE) of Qin and Lawless (1994).
Hyungtaik Ahn, Yuichi Kitamura, Gautam Tripathi   +2 more
core  

On the Distribution of Likelihood Ratio Test Statistics for Cointegration Rank

Econometric Reviews, 2004
Abstract This paper analyses the likelihood ratio test for the hypothesis of reduced cointegration rank in a Gaussian vector autoregressive model. The usual asymptotic distribution typically gives rather large size distortions. This is explained by the fact that the asymptotic distribution of the likelihood ratio test statistic varies across the ...
openaire   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source