Results 111 to 120 of about 101,218 (287)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Goodness of Fit Test and Test of Independence by Entropy

open access: yesJournal of Mathematical Extension, 2009
To test whether a set of data has a specific distribution or not, we can use the goodness of fit test. This test can be done by one of Pearson X 2 -statistic or the likelihood ratio statistic G 2 , which are asymptotically equal, and also by using
M. Sharifdoost, N. Nematollahi, E. Pasha
doaj  

Improved Likelihood Ratio Statistics for Generalized Linear Models

open access: yesJournal of the Royal Statistical Society Series B: Statistical Methodology, 1983
Summary This paper gives a general formula for the expected value of the likelihood ratio statistic for generalized linear models, corrected up to terms of order n  -1, where n is the size of the sample. The application of this formula to some models is illustrated.
openaire   +2 more sources

"Empirical Likelihood Methods in Econometrics: Theory and Practice" [PDF]

open access: yes
Recent developments in empirical likelihood (EL) methods are reviewed. First, to put the method inperspective, two interpretations of empirical likelihood are presented, one as a nonparametric maximum likelihood estimation method (NPMLE) and the other as
Yuichi Kitamura
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

The Bayesian Score Statistic

open access: yes
We propose a novel Bayesian test under a (noninformative) Jeffreys' prior specification. We check whether the fixed scalar value of the so- called Bayesian Score Statistic (BSS) under the null hypothesis is a plausible realization from its known and ...
Kleijn, R.H., Kleibergen, F.R., Paap, R.
core   +2 more sources

Empirical likelihood confidence regions of the parameters in a partially single-index varying-coefficient model

open access: yesOpen Mathematics, 2019
In this paper, we investigate a partially single-index varying-coefficient model, and suggest two empirical log-likelihood ratio statistics for the unknown parameters in the model.
Xiang Xing, Liu Wanrong
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Non-null Distribution of The Likelihood Ratio Statistic for Testing Multisample Compound Symmetry

open access: yes, 2022
The non-null distribution of the modified likelihood ratio test statistic Λ∗ for testing multisample compound symmetry of q multivariate Gaussian models is derived.
Castañeda, María E., Nagar, Daya K.
core   +1 more source

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