Results 91 to 100 of about 10,105,993 (275)
SUMMARY This paper characterizes priors under which the Bayesian and frequentist Bartlett corrections for the likelihood ratio and the conditional likelihood ratio (CLR) statistics differ by o(1). It is seen that, except for sample points with negligible probability, the CLR statistic has a posterior distribution for which a posterior ...
Ghosh, J. K., Mukerjee, Rahul
openaire +2 more sources
A Novel Ship Detector Based on the Generalized-Likelihood Ratio Test for SAR Imagery
Ship detection with synthetic aperture radar (SAR) images, acquired at different working frequencies, is presented in this paper where a novel technique is proposed based on the generalized-likelihood ratio test (GLRT).
Pasquale Iervolino, Raffaella Guida
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
The statistical analysis of circular, multivariate circular, and spherical data is very important in different areas, such as paleomagnetism, astronomy and biology.
Juan José Fernández-Durán +1 more
doaj +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Likelihood Ratio Tests for Multiply Imputed Datasets: Introducing milrtest [PDF]
Through the use of user-written programs, primarily mim (Carlin, Galati, and Royston, 2008), Stata users can analyze multiply imputed (MI) datasets. Among other capabilities, mim allows the user to estimate a range of regression models and to perform a ...
Rose Medeiros
core

