Likelihood ratio test for genetic association study with case-control data under Probit model. [PDF]
J Appl Stat, 2022 Sheng Z, Liu Y, Li P, Qin J.
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Real-Time Detection of Incipient Inter-Turn Short Circuit and Sensor Faults in Permanent Magnet Synchronous Motor Drives Based on Generalized Likelihood Ratio Test and Structural Analysis. [PDF]
Sensors (Basel), 2022 Hasan Ebrahimi S, Choux M, Huynh VK.
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Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
On the Likelihood Ratio Test of a Normal Multivariate Testing Problem II
The Annals of Mathematical Statistics, 1964 Let the random vector $X = (X_1 \cdots X_p)'$ have a multivariate normal distribution with unknown mean $\xi = (\xi_1 \cdots \xi_p)'$ and unknown nonsingular covariance matrix $\Sigma$. Write $\Sigma^{-1}\xi = \Gamma = (\Gamma_1 \cdots \Gamma_p)'$. The problem considered here is that of testing the hypothesis $H_0 : \Gamma_{q + 1} = \cdots = \Gamma_p =
openaire +4 more sources
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
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A Likelihood Ratio Test for Gene-Environment Interaction Based on the Trend Effect of Genotype Under an Additive Risk Model Using the Gene-Environment Independence Assumption. [PDF]
Am J Epidemiol, 2021 de Rochemonteix M +8 more
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Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
A Novel Decoder for Unknown Diversity Channels Employing Space-Time Codes
EURASIP Journal on Advances in Signal Processing, 2002 We suggest new decoding techniques for diversity channels employing space time codes (STC) when the channel coefficients are unknown to both transmitter and receiver.
Erez Elona, Feder Meir
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