Results 41 to 50 of about 643,997 (233)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman +9 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad +9 more
wiley +1 more source
Power analysis for RNA-Seq differential expression studies
BMC Bioinformatics, 2017 Background Sample size calculation and power estimation are essential components of experimental designs in biomedical research. It is very challenging to estimate power for RNA-Seq differential expression under complex experimental designs.
Lianbo Yu, Soledad Fernandez, Guy Brock
doaj +1 more source
Likelihood Ratio Testing under Measurement Errors [PDF]
Entropy, 2018 We consider the likelihood ratio test of a simple null hypothesis (with density f 0 ) against a simple alternative hypothesis (with density g 0 ) in the situation that observations X i are mismeasured due to the presence of measurement errors.
Broniatowski, Michel +2 more
openaire +6 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen +10 more
wiley +1 more source
Inflated Kumaraswamy distributions
Anais da Academia Brasileira de Ciências, 2019 : The Kumaraswamy distribution is useful for modeling variables whose support is the standard unit interval, i.e., (0, 1). It is not uncommon, however, for the data to contain zeros and/or ones.
FRANCISCO CRIBARI-NETO, JÉSSICA SANTOS
doaj +1 more source
Statistical Inference for Odds Ratio of Two Proportions in Bilateral Correlated Data
Axioms, 2022 Bilateral correlated data frequently arise in medical clinical studies such as otolaryngology and ophthalmology. Based on an equal correlation coefficient model, this paper mainly aimed to investigate the statistical inference for the odds ratio of two ...
Zhiming Li, Changxing Ma
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess +5 more
wiley +1 more source
Giornale di Clinica Nefrologia e Dialisi, 2016 non disponibile (Epidemiology_statistics)
Francesco Franco, Anteo Di Napoli
doaj +1 more source
On the Likelihood Ratio Tests in Bivariate ACDE Models [PDF]
Psychometrika, 2013 The ACE and ADE models have been heavily exploited in twin studies to identify the genetic and environmental components in phenotypes. However, the validity of the likelihood ratio test (LRT) of the existence of a variance component, a key step in the use of such models, has been doubted because the true values of the parameters lie on the boundary of ...
Wu, Hao, Neale, Michael C.
openaire +2 more sources