Results 61 to 70 of about 10,105,993 (275)
On the Likelihood Ratio Tests in Bivariate ACDE Models [PDF]
The ACE and ADE models have been heavily exploited in twin studies to identify the genetic and environmental components in phenotypes. However, the validity of the likelihood ratio test (LRT) of the existence of a variance component, a key step in the use of such models, has been doubted because the true values of the parameters lie on the boundary of ...
Wu, Hao, Neale, Michael C.
openaire +2 more sources
Type-1 Beta Distribution and its Connections to Likelihood Ratio Test
In many cases involving hypothesis testing for parameters in multivariate Gaussian populations and certain other populations, likelihood ratio criteria, or their one-to-one functions, can be expressed in terms of the determinant of a real type-1 beta ...
Nicy Sebastian, T. Princy
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Sequential Likelihood Ratio Test for Cognitive Radios [PDF]
This paper presents a sequential likelihood ratio test (SLRT) detector for spectrum sensing scenarios in cognitive radios (CRs). Similar to other CR detectors, we exploit the structure of the sample covariance matrix of the received signal to achieve detection with minimal information regarding the signal.
Julien Renard +2 more
openaire +2 more sources
Likelihood inference for small variance components
In this paper, we develop likelihood-based methods for making inferences about the components of variance in a general normal mixed linear model. In particular, we use local asymptotic approximations to construct confidence intervals for the components ...
Stern, S.E., Welsh, A.H.
core +1 more source
Background : Current amblyopia screening methods are not cost effective. Aim : To evaluate the diagnostic capability of a modified Brückner test (MBT) for amblyopiogenic risk factors.
Abadan Khan Amitava +3 more
doaj +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source

