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Acute Limb Ischemia

open access: yesAnnals of Vascular Diseases, 2018
Acute limb ischemia (ALI) is a rapid decrease in lower limb blood flow due to acute occlusion of peripheral artery or bypass graft, and in ALI not only limbs but also life prognosis will be poor unless quick and appropriate treatment is given. The etiology is broadly divided into embolism and thrombosis with various comorbidities.
Hideaki Obara   +2 more
semanticscholar   +8 more sources

Pathophysiology of chronic limb ischemia [PDF]

open access: yesGefässchirurgie, 2018
Chronic ischemia of the lower extremities is an everyday problem in vascular surgery clinics. In Germany, approximately 3% of all hospitalizations are due to peripheral artery disease (PAD), with critical limb ischemia (CLI) in particular showing a rapid increase.
P. Düppers   +5 more
openaire   +4 more sources

Critical limb ischemia [PDF]

open access: yesVascular Medicine, 2021
Critical limb ischemia (CLI), also known as chronic limbthreatening ischemia (CLTI), is the most severe form of peripheral artery disease (PAD). PAD occurs due to blockages in the leg arteries due to atherosclerosis or plaque build-up.
Ehrin J Armstrong, David G Armstrong
openaire   +4 more sources

Emerging roles of mesenchymal stem cell therapy in patients with critical limb ischemia

open access: yesStem cell research & therapeutics, 2022
Critical limb ischemia (CLI), the terminal stage of peripheral arterial disease (PAD), is characterized by an extremely high risk of amputation and vascular issues, resulting in severe morbidity and mortality.
Zeinab Shirbaghaee   +3 more
semanticscholar   +1 more source

Surgery or Endovascular Therapy for Chronic Limb-Threatening Ischemia.

open access: yesNew England Journal of Medicine, 2022
BACKGROUND Patients with chronic limb-threatening ischemia (CLTI) require revascularization to improve limb perfusion and thereby limit the risk of amputation.
A. Farber   +43 more
semanticscholar   +1 more source

Exosomes derived from adipose-derived stem cells overexpressing glyoxalase-1 protect endothelial cells and enhance angiogenesis in type 2 diabetic mice with limb ischemia

open access: yesStem cell research & therapeutics, 2021
Diabetic limb ischemia is a clinical syndrome and refractory to therapy. Our previous study demonstrated that adipose-derived stem cells (ADSCs) overexpressing glyoxalase-1 (GLO-1) promoted the regeneration of ischemic lower limbs in diabetic mice, but ...
Xing Zhang   +10 more
semanticscholar   +1 more source

Comparative analysis of mouse bone marrow and adipose tissue mesenchymal stem cells for critical limb ischemia cell therapy

open access: yesStem cell research & therapeutics, 2021
Introduction Critical limb ischemia (CLI) is the most advanced form of peripheral arterial disease (PAD) characterized by ischemic rest pain and non-healing ulcers.
Pegah Nammian   +5 more
semanticscholar   +1 more source

Acute limb ischaemia in a young male with secondary polycythaemia: A case report

open access: yesRadiology Case Reports, 2023
Acute limb ischemia is a life and limb-threatening pathology rarely observed in young populations. One of the uncommon causes includes hypercoagulable state which can occur in secondary polycythemia leading to an abnormal increase in the erythrocyte mass.
Cheuk Tung Kam, MB ChB   +3 more
doaj   +1 more source

Missing limb ischemia in dark-skinned patients: The badinjal sign

open access: yesIndian Journal of Vascular and Endovascular Surgery, 2021
Limb ischemia is acute, chronic, or acute on chronic, and the prevalence of the latter is rising with the presence of an increasing aging population. When occlusion to the flow of blood is sudden, it results in acute limb ischemia, the early diagnosis of
Edwin Stephen   +4 more
doaj   +1 more source

Achieving Functional Outcomes after Surgical Management of Catastrophic Vasopressor-induced Limb Ischemia

open access: yesPlastic and Reconstructive Surgery, Global Open, 2022
Background:. Vasopressor-induced limb ischemia is an unfortunate complication that can occur in patients treated for septic shock. Current literature lacks surgical treatment recommendations for this condition, besides amputation.
Romina Deldar, MD   +6 more
doaj   +1 more source

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