Results 31 to 40 of about 922,275 (357)

The burden of critical limb ischemia: a review of recent literature

Vascular Health and Risk Management, 2019
Peripheral arterial disease is a chronic vascular disease characterized by impaired circulation to the lower extremities. Its most severe stage, known as critical limb ischemia (CLI), puts patients at an increased risk of cardiovascular events ...
S. Duff, M. Mafilios, P. Bhounsule, J. Hasegawa   +3 more
semanticscholar   +1 more source

Neonatal acute limb ischemia

Journal of Pediatric Surgery Case Reports, 2021
Acute limb ischemia is a rare disorder in the perinatal period. The etiology and management of acute limb ischemia is not well described. We report 4 cases of acute limb ischemia in the neonatal period.
Rebecca Bonny-Obro, Yapi Landry Aké, Kokoe Midekor-Gonebo, Amenan Kan Kouassi-Dria, Sigue Jean Ouattara, Moufidath Sounkere-Soro, Kokora Xavier Dibi, Ello Nicolas Moh   +7 more
doaj   +1 more source

Acute Limb Ischemia: An Update on Diagnosis and Management

Journal of Clinical Medicine, 2019
This review presents an update on the diagnosis and management of acute limb ischemia (ALI), a severe condition associated with high mortality and amputation rates. A comprehensive spectrum of ALI etiology is presented, with highlights on embolism and in
D. Olinic, Agata Stanek, Dan Tataru, C. Homorodean, M. Olinic   +4 more
semanticscholar   +1 more source

E-Selectin/AAV2/2 Gene Therapy Alters Angiogenesis and Inflammatory Gene Profiles in Mouse Gangrene Model

Frontiers in Cardiovascular Medicine, 2022
For patients with chronic limb-threatening ischemia and limited revascularization options, alternate means for therapeutic angiogenesis and limb salvage are needed.
Antoine J. Ribieras, Yulexi Y. Ortiz, Yan Li, Carlos T. Huerta, Nga Le, Hongwei Shao, Roberto I. Vazquez-Padron, Roberto I. Vazquez-Padron, Zhao-Jun Liu, Zhao-Jun Liu, Omaida C. Velazquez, Omaida C. Velazquez   +11 more
doaj   +1 more source

Combination of Antioxidant Enzyme Overexpression and N‐Acetylcysteine Treatment Enhances the Survival of Bone Marrow Mesenchymal Stromal Cells in Ischemic Limb in Mice With Type 2 Diabetes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Therapy with mesenchymal stem cells remains a promising but challenging approach to critical limb ischemia in diabetes because of the dismal cell survival.
Qiang Zhu, Hong Hao, Huifang Xu, Yosef Fichman, Yuqi Cui, Chunlin Yang, Meifang Wang, Ron Mittler, Michael A. Hill, Peter J. Cowan, Guangsen Zhang, Xiaoming He, Shenghua Zhou, Zhenguo Liu   +13 more
doaj   +1 more source

Reservoir of Fibroblasts Promotes Recovery From Limb Ischemia

Circulation, 2020
Supplemental Digital Content is available in the text. Background: The angiogenic response to ischemia restores perfusion so as to preserve tissue. A role for mesenchymal-to-endothelial transition in the angiogenic response is controversial.
Shu Meng, Jie Lv, P. Chanda, I. Owusu, Kaifu Chen, J. Cooke   +5 more
semanticscholar   +1 more source

Therapeutic Angiogenesis for Severely Ischemic Limbs — from Bench to Bedside in Acute Vascular Care

Journal of Cardiovascular Emergencies, 2017
Severe limb ischemia represents a critical condition, being associated with high morbidity and mortality rates. Patients with critical limb ischemia (CLI) require urgent initiation of interventional or surgical treatment, as restoration of the blood flow
Benedek Theodora, Kovács István, Benedek Imre   +2 more
doaj   +1 more source

Two effective cases of additional pedal artery angioplasty for severe lower limb ischemia following acute thrombotic artery occlusion with hypercoagulable state diseases

CVIR Endovascular, 2020
Background Acute limb ischemia (ALI) and critical limb ischemia (CLI) following ALI are life-threatening diseases. The rare potential causes of ALI include hypercoagulable state diseases, such as antiphospholipid syndrome (APS) and essential ...
Keisuke Shoji, Kan Zen, Kenji Yanishi, Noriyuki Wakana, Naohiko Nakanishi, Takeshi Nakamura, Satoaki Matoba   +6 more
doaj   +1 more source

Vasospastic Limb Ischemia Presenting Acute and Chronic Limb Ischemia

Annals of Vascular Diseases, 2014
Vasospastic limb ischemia might have been underappreciated compared to vasospasm in other territories such as heart and brain. However, an increasing awareness of this vascular disorder can be translated to an improved patients' care. Herein, we report a case of vasospasm presenting acute and chronic limb ischemia in four extremities.
Satoshi Yasuda, Shingo Sakamoto, Masaharu Ishihara, Koichiro Harada, Osami Kawarada, Junji kaneyama, Hisao Ogawa   +6 more
openaire   +4 more sources

Perfusion Assessment in Critical Limb Ischemia: Principles for Understanding and the Development of Evidence and Evaluation of Devices: A Scientific Statement From the American Heart Association.

Circulation, 2019
There are >12 million patients with peripheral artery disease in the United States. The most severe form of peripheral artery disease is critical limb ischemia (CLI). The diagnosis and management of CLI is often challenging.
S. Misra, M. Shishehbor, E. Takahashi, H. Aronow, L. Brewster, M. Bunte, E. Kim, J. Lindner, K. Rich   +8 more
semanticscholar   +1 more source