Results 71 to 80 of about 922,275 (357)
Advanced Science, EarlyView.This study reveals that the glycolytic enzyme HK2 mediates hypoxia‐induced astrocytic exosome biogenesis by directly phosphorylating nSMase1. These astrocytic exosomes impair brain endothelial tight junctions. Astrocyte‐specific knockdown of HK2 reduces exosome release and alleviates brain injury after MCAO.
Chen Chen +12 more
wiley +1 more source
Surgical extremity preservation in severe acute limb ischemia in a 4-week-old newborn
Annals of Vascular Surgery - Brief Reports and InnovationsThis case report describes a successful revascularisation of severe acute limb ischemia (ALI) in a 4-week-old newborn following common femoral artery dissection due to catheterization for invasive blood pressure measurement during cardiac arrest in the ...
Manuela Schulz +5 more
doaj +1 more source
A neonate with spontaneous arterial limb ischemia and an aneurysm of the oval foramen: a case report
Journal of Medical Case Reports, 2021 Background In this case report, we describe a very rare case of severe limb ischemia due to an arterial embolus caused by an aneurysm of the oval foramen in a term-born infant that occurred in the first few hours after birth.
J. J. van Vonderen +5 more
doaj +1 more source
Chronic Critical Limb Ischemia [PDF]
Deutsches Ärzteblatt international, 2012 Some 40 000 lower limb amputations are performed in Germany each year, 70% of them in diabetics. About 80% of all major amputations may be preventable with the use of new interventional and vascular surgical procedures, particularly on the arteries of the leg and foot. We present the current state of the art in revascularization techniques and evaluate
Dohmen, Arndt +4 more
openaire +4 more sources
Current Treatment Options in Acute Limb Ischemia
RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 2019 Background Acute limb ischemia represents a clinical emergency with eventual limb loss and life-threatening consequences. It is characterized by a sudden decrease in limb perfusion.
Friederika Fluck +3 more
semanticscholar +1 more source
Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation
Advanced Science, EarlyView.LPS‐induced systemic inflammation increases glymphatic influx but delays cervical lymphatic drainage, accompanied by AQP4 depolarization and impaired glymphatic clearance. Enhancing cerebral blood flow via the inotropic agent levosimendan effectively restored AQP4 polarization, improving glymphatic flux and amyloid‐β clearance.
Ruoyu Zhao +9 more
wiley +1 more source
BMC Cardiovascular DisordersBackground and objectives Venous-Arterial Extracorporeal Membrane Oxygenation (VA-ECMO) is a pivotal means for rapid cardiopulmonary support, yet it may result in lower limb ischemia.
Zhenjia Liu +5 more
doaj +1 more source
Resuscitation PlusObjectives: Lower limb ischemia after extracorporeal life support for refractory cardiac arrest may be prevented by effective distal perfusion catheter (DPC) placement.
Sebastian Voicu +9 more
doaj +1 more source
Iatrogenic lower limb ischemia in children with congenital cardiac disease
Indian Journal of Vascular and Endovascular Surgery, 2018 Aim: To report our experience of the management of peripheral artery cannulation-induced limb ischemia in neonates, infants, and children (
Bhavin L Ram, S Rajesh, Robbie K George
doaj +1 more source
Experimental and Molecular Medicine, 2023 Despite recent progress in medical and endovascular therapy, the prognosis for patients with critical limb ischemia (CLI) remains poor. In response, various stem cells and growth factors have been assessed for use in therapeutic neovascularization and ...
Jin-Ju Kim +11 more
doaj +1 more source