Results 91 to 100 of about 308,349 (254)

Horrifying Basal Cell Carcinoma Presenting as Progressive Pyoderma Gangrenosum: Case Report

Case Reports in Oncology
Introduction: Skin ulcers can be challenging to diagnose and manage, particularly with comorbid autoimmune and gastrointestinal diseases. Occam’s razor encourages the simplest explanation to guide care, but reconsideration must occur when intervention ...
Jason S. Hoellwarth, Taylor J. Reif, Shoko Mori, Rachel Kang, Cynthia M. Magro   +4 more
doaj   +1 more source

Peripheral nerve damage during limb lengthening. Neurophysiology in five cases of bilateral tibial lengthening

, 1990
Limb lengthening is used to correct leg length discrepancy and to increase stature. The reported frequency of peripheral nerve complications varies from 5% to 30%, but is probably underestimated.
A Paronzini, R Facchini, M Novarina, G Comi, L Lozza, P Marchettini, G Galardi   +6 more
core   +1 more source

Intramedullary Bone Lengthening Following Preceding Hip Surgery—A Case Series

, 2020
Limb length discrepancy (LLD) is a common problem after joint-preserving hip surgeries, hip dysplasia, and hip deformities. Limping, pain, sciatica, paresthesia, and hip instability are common clinical findings and may necessitate limb-lengthening ...
Gerald Eliot Wozasek, Lukas Zak, Thomas Manfred Tiefenboeck   +2 more
core   +1 more source

Tibial Lengthening Using a Fixator-Assisted Lengthening Plate: A New Technique [PDF]

, 2016
Background: There are many techniques that are used for limb lengthening. Lengthening a limb over a plate is an alternative choice used in children or when using an intramedullary nail is difficult. Objectives: In this study, we presented a new technique
Agir, Ismail, Tosun, Haci Bayram, Serbest, Sancar, Uludag, Abuzer, Celik, Suat, Gumustas, Seyitali   +5 more
core   +1 more source

A Microenvironment‐Adaptive Scaffold Rejuvenates Peripheral Nerve Regeneration During Aging Via Dual Modulation of Ferroptotic Stimuli in Schwann Cells

Advanced Science, EarlyView.
(i) Aging impairs peripheral nerve regeneration via its dual ferroptosis‐mediated pathologies in senescent schwann cells. (ii) The composite nerve conduit is a symbiosis niche integrating microenvironment‐responsive nanoparticles (Ga‐PTAs) and maxillofacial‐derived mesenchymal stem cells (Mmscs).
Ning Zhan, Lixin Tian, Lianjie Peng, Jingyu Zhang, Lining Lin, Xiaoting Zhang, Yaxian Luo, Zhichao Liu, Xinhua Yao, Mouyuan Sun, Yong He, Mengfei Yu, Huiming Wang   +12 more
wiley   +1 more source

Development of an evidence-based diagnostic algorithm for infection in patients with transcutaneous osseointegration following amputation [PDF]

Journal of Bone and Joint Infection
Introduction: Transcutaneous osseointegration following amputation (TOFA) confers better mobility and quality of life for most patients versus socket prosthesis rehabilitation.
S. H. Alam, J. S. Hoellwarth, K. Tetsworth, A. Oomatia, T. N. Taylor, M. Al Muderis   +5 more
doaj   +1 more source

Multi‐Technique Integration Identifies O‐GlcNAc Transferase in Fibroblast‐Like Synoviocytes as a Therapeutic Target for Rheumatoid Arthritis

Advanced Science, EarlyView.
AI‑guided single‑cell transcriptomics identifies OGT as a key regulator enriched in rheumatoid arthritis fibroblast‑like synoviocytes (RA‐FLSs). Inflammatory stimuli activate the OGT–SAP130 axis, which modulates the H3K27ac/H3K27me3 balance and epigenetically silences BTG2, promoting aggressive transformation of RA‑FLSs.
Duoli Xie, Jie Huang, Chunhao Cao, Zhenchao Tang, Xingchen Li, Jianmin Guo, Xinxin Chen, Fang Wang, Dongyi He, Jie Li, Yu Du, Bing He, Jianhua Yao, Aiping Lu, Chao Liang   +14 more
wiley   +1 more source

Limb lengthening using ankle joint distraction (arthrodiastasis) followed by arthrodesis. Experience with one case

, 2011
Tibial aplasias are difficult entities to manage and sometimes require significant limb lengthening. Preserving the joint is the preferred option in these cases.
Jacquemier, Jocelyne, Bollini, Gérard, J.-L. Jouve, Jacopin, Samuel, G. Bollini, Blondel, Benjamin, M. Jacquemier, F. Launay, Launey, Franck, Jouve, Jean-Luc, S. Jacopin, B. Blondel   +11 more
core   +1 more source

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

Advanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu, Xue Han, Heng Zhang, Chang Ye, Tianjiao Xia, Xiaoping Gu   +5 more
wiley   +1 more source

Antibiotic-Coated Intramedullary Nailing Managing Long Bone Infected Non-Unions: A Meta-Analysis of Comparative Studies

Antibiotics
Long bone infected non-unions are such an orthopedic challenge that antibiotic-coated intramedullary nailing (ACIN) has become a viable therapeutic option for their management.
Amirhossein Ghaseminejad-Raeini, Alireza Azarboo, Kasra Pirahesh, Amirmohammad Sharafi, Amir Human Hoveidaei, Basilia Onyinyechukwu Nwankwo, Abhijith Annasamudram, Janet D. Conway   +7 more
doaj   +1 more source