Results 181 to 190 of about 48,368 (252)

Defining sagittal knee phenotypes via monopedal static anterior tibial translation. Part 1: Translating weight‐bearing sagittal position into clinical risk profiles

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Static anterior tibial translation (sATT) is a reproducible monopodal weight‐bearing radiographic parameter that reflects the resting sagittal position of the tibiofemoral joint. Distinct from manual laxity tests that quantify passive displacement limits, sATT captures the functional equilibrium of the tibia under physiological load ...
Mahmut Enes Kayaalp, Hamit Caglayan Kahraman, Tunay Erden, Christoph Lutter, Sven Scheffler, Omer Taser, Roland Becker, Michael T. Hirschmann, David H. Dejour   +8 more
wiley   +1 more source

Defining sagittal knee phenotypes via monopedal static anterior tibial translation. Part 2: The assessment‐led personalization (ALP) system for indication and correction target planning in slope‐reducing osteotomy

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Current decision‐making for slope‐reducing osteotomy (SRO) often relies on isolated posterior tibial slope (PTS) thresholds, potentially misidentifying patients with acquired soft‐tissue decompensation or possibly overtreating those with an asymptomatic, inherently hyperlax baseline.
Mahmut Enes Kayaalp, Hamit Caglayan Kahraman, Tunay Erden, Christoph Lutter, Sven Scheffler, Omer Taser, Roland Becker, Michael T. Hirschmann, David H. Dejour   +8 more
wiley   +1 more source

Chick Limb Regeneration [PDF]

Science, 2012
openaire   +1 more source

Heterogenous Neuropathology in a Pedigree with RAB39B‐Related Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background In 2015, we reported a family with Parkinson's disease resulting from the RAB39B p.G192R (c.574G>A) variant. Since then, two affected brothers from the family have undergone autopsy. Objectives To characterize neuropathological findings, assess intracellular distribution of RAB39B protein, and examine the effect of p.G192R on α ...
Caitlin Latimer, Oswaldo Lorenzo‐Betancor, Dong‐Hui Chen, Kimmy Su, Marika Bogdani, Anna J. Park, Minsuh Kim, Joshua Weiss, Malia Callier, Ella H. Chiu, Sarah Fish, Jennifer L. Witt, Wendy H. Raskind, Marie Y. Davis, C. Dirk Keene, Cyrus P. Zabetian   +15 more
wiley   +1 more source

SPG4 Hereditary Spastic Paraplegia: From Etiology to Therapy

Movement Disorders, EarlyView.
Abstract Hereditary spastic paraplegias (HSPs) comprise a heterogeneous group of heritable neurodegenerative disorders resulting from mutations in a wide variety of genes. HSP locomotor symptoms include lower limb weakness and spasticity that arise from progressive degeneration of corticospinal axons projecting from the motor cortex to the distal ...
Emanuela Piermarini, Peter W. Baas
wiley   +1 more source

Functional rescue of critical-size bone defect using molecular network analysis of axolotl limb regeneration

Polikarpova A, Rivero-Garcia I, Gerber T, Wang J, Novatchkova M, Fischer A, Torres M, Sánchez-Cabo F, Tanaka E.   +8 more
europepmc   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

AGRN‐, LRP4‐, MUSK‐Related CMS: Clinical, Neurophysiological, Morphological, Genetic and Pathological Mechanisms

Muscle &Nerve, EarlyView.
ABSTRACT Congenital myasthenic syndromes (CMS) are inherited disorders caused by mutations in genes encoding proteins essential for neuromuscular junction (NMJ) function. Pathogenic variants have been identified in more than 35 genes, underscoring the complexity of synaptic biology and the wide range of mechanisms that can compromise neuromuscular ...
Rocio‐Nur Villar‐Quiles, Damien Sternberg, Marie‐Christine Nougues, Arnaud Isapof, Bruno Eymard, Stéphanie Bauché   +5 more
wiley   +1 more source

Mechanical control of tissue growth during limb regeneration

Edwards-Jorquera S, Ceccarelli A, Schlüßler R, Murali Shankar N, Muñoz Ovalle A, Gentleman K, Freudenberg U, Werner C, Chara O, Taubenberger A, Sandoval-Guzmán T.   +10 more
europepmc   +1 more source

Hierarchical pattern formation during amphibian limb regeneration. [PDF]

Biosystems, 2019
Vieira WA, McCusker CD.
europepmc   +1 more source