Streptozotocin induced hyperglycemia in the axolotl. [PDF]
Dev DynAbstract Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration.
Sørensen PL, Dittrich A, Lauridsen H.
europepmc +5 more sources
High-dimensional co-expression network analysis reveals persistent TRH gene expression throughout axolotl telencephalon regeneration [PDF]
Frontiers in BioinformaticsIntroductionThe Axolotl (Ambystoma mexicanum) offers a deep insight into brain regeneration by fully reconstructing its telencephalon post-injury, a capability that most vertebrates do not have.
Iveth Gómez-Morales +4 more
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Revealing the biological features of the axolotl pancreas as a new research model
Frontiers in Cell and Developmental BiologyIntroductionThe pancreas plays a crucial role in digestion and blood glucose regulation. Current animal models, primarily mice and zebrafish, have limited the exploration of pancreatic biology from an evolutionary-developmental perspective.
Liu Yanmei, Pan Xiangyu
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Limb Regeneration in Axolotl: Is It Superhealing? [PDF]
Scientific World Journal, The, 2006 The ability of axolotls to regenerate their limbs is almost legendary. In fact, urodeles such as the axolotl are the only vertebrates that can regenerate multiple structures like their limbs, jaws, tail, spinal cord, and skin (the list goes on) throughout their lives.
Stéphane Roy +2 more
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Influence of semicircular canal morphology on the VOR and swimming activity in larval amphibians: a comparative study in Xenopus and axolotl [PDF]
Frontiers in NeurologyGaze stabilization and locomotion rely often on an accurate sensory detection of head movements by the vestibular system. A functional relationship between vestibular sensitivity, locomotor skills and semicircular canal morphology has been suspected in ...
Parthena Schneider-Soupiadis +10 more
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A comparative transcriptomics analysis of mammalian and non-mammalian acute kidney injury (AKI) models [PDF]
Frontiers in Cell and Developmental BiologyIntroductionAcute kidney injury (AKI) is a complex clinical condition characterized by decline in renal function and widespread transcriptional dysregulation. While transcriptomic studies that compare human and other mammalian models of AKI have provided
Matthew R. Hawkins +3 more
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A mammalian-like piRNA pathway in Axolotl reveals the origins of piRNA-directed DNA methylation [PDF]
The EMBO JournalThe piRNA pathway protects animal germlines from active transposons. Mammals employ a cytoplasmic pathway to destroy transposon transcripts during germline reprogramming.
Xinyu Xiang +8 more
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Neuronal activation in the axolotl brain promotes tail regeneration [PDF]
npj Regenerative MedicineThe axolotl retains a remarkable capacity for regenerative repair and is one of the few vertebrate species capable of regenerating its brain and spinal cord after injury.
SE Walker +3 more
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Management of Hydrocoelom in an Axolotl (Ambystoma mexicanum) [PDF]
Veterinary Medicine and ScienceA 3‐year‐old axolotl (Ambystoma mexicanum) presented with anorexia, weakness and abdominal swelling due to hydrocoelom. According to the anamnesis, the symptoms had occurred 3 months prior. The radiographic and ultrasonographic examinations revealed that
Şeyma Sueda Cirit +3 more
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eLife, 2022 The expression of fibroblast growth factors (Fgf) ligands in a specialized epithelial compartment, the Apical Ectodermal Ridge (AER), is a conserved feature of limb development across vertebrate species.
Giacomo L Glotzer +2 more
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