Results 41 to 50 of about 3,132 (177)
DIPLOID GYNOGENESIS IN THE MEXICAN AXOLOTL [PDF]
Genetics, 1976 ABSTRACT Gynogenetic diploid axolotls were produced by activating eggs with ultraviolet-inactivated sperm, and then subjecting the activated eggs to heat shock. Optimal conditions for ultraviolet inactivation of the sperm, and for suppression of the second meiotic division by heat shock, were established. Gynogenetic diploids produced by
T M, Trottier, J B, Armstrong
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The Anatomical Record, Volume 309, Issue 8, Page 2151-2175, August 2026.Abstract Scientists have been captivated by the ability to regenerate, focusing on uncovering the mechanisms of epimorphic regeneration and applying them to human medicine. The axolotl (Ambystoma mexicanum) has become the most intensively studied model in tetrapod regeneration research, particularly concerning limb regeneration.
Vivien Bothe, Nadia Fröbisch
wiley +1 more source
Inducible genetic system for the axolotl [PDF]
Proceedings of the National Academy of Sciences, 2012 Transgenesis promises a powerful means for assessing gene function during amphibian limb regeneration. This approach is complicated, however, by the need for embryonic appendage development to proceed unimpeded despite the genetic alterations one wishes to test later in the context of regeneration.
Jessica L, Whited +2 more
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Advanced Science, Volume 13, Issue 41, 22 July 2026.We establish a tBid‐mediated cell ablation system in axolotls, achieve rapid and efficient ablation of multiple cell types, including muscle stem cell, spinal cord cell, and connective tissue (CT) cells. We investigate the role of CT using tBid‐mediated CT ablation and identify its essential role for limb development and regeneration.
Yan Hu +11 more
wiley +1 more source
PLoS Biology, 2023 Pluripotency defines the unlimited potential of individual cells of vertebrate embryos, from which all adult somatic cells and germ cells are derived. Understanding how the programming of pluripotency evolved has been obscured in part by a lack of data ...
Luke A Simpson +14 more
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Biopolymers, Volume 117, Issue 4, July 2026.The preparation and characterization of metronidazole loaded chitosan and alginate gels, followed by polyelectrolyte complex formation and 3D printing of multilayer periodontal films. ABSTRACT This study aimed to prepare six different metronidazole‐loaded film formulations by 3D printing for periodontal treatment.
Dicle Denizhan +5 more
wiley +1 more source
Proteome data to explore the axolotl limb regeneration capacity at neotenic and metamorphic stages
Data in Brief, 2020 The presented data article reports protein expression profiles during a time course of limb regeneration in the highly regenerative neotenic and regeneration-deficient metamorphic axolotl (Ambystoma mexicanum). A protein database was first generated from
Turan Demircan +2 more
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Genomics and epigenomics of axolotl regeneration
The International Journal of Developmental Biology, 2021 The axolotl ( Ambystoma mexicanum) has been a widely studied organism due to its capacity to regenerate most of its cells, tissues and whole-body parts. Since its genome was sequenced, several molecular tools have been developed to study the mechanisms behind this outstanding and ...
Cynthia, Sámano +6 more
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Interdisciplinary Medicine, Volume 4, Issue 4, July 2026.The developing bone was identified as an M2a‐like macrophage driven immune microenvironment with multidimensional developmental signatures. hME‐ApoEVs were successfully fabricated via stimulating the M2a‐like developing microenvironment in vitro and confirmed its recapitulation of developmental features.
Xiaoran Yu +11 more
wiley +1 more source