Results 51 to 60 of about 3,132 (177)

Establishing an Efficient Electroporation-Based Method to Manipulate Target Gene Expression in the Axolotl Brain

open access: yesCell Transplantation, 2023
The tetrapod salamander species axolotl ( Ambystoma mexicanum ) is capable of regenerating injured brain. For better understanding the mechanisms of brain regeneration, it is very necessary to establish a rapid and efficient gain-of-function and loss-of ...
Sulei Fu   +5 more
doaj   +1 more source

A Morphological and Histological Investigation of Imperfect Lungfish Fin Regeneration

open access: yesFrontiers in Ecology and Evolution, 2021
Regeneration, the replacement of body parts in a living animal, has excited scientists for centuries and our knowledge of vertebrate appendage regeneration has increased significantly over the past decades.
Vivien Bothe   +3 more
doaj   +1 more source

Muscles are barely required for the patterning and cell dynamics in axolotl limb regeneration

open access: yesFrontiers in Genetics, 2022
Regeneration of a complex appendage structure such as limb requires upstream and downstream coordination of multiple types of cells. Given type of cell may sit at higher upstream position to control the activities of other cells.
Yan Hu   +11 more
doaj   +1 more source

Bilayer Wound Dressing Based on Green‐Synthesized ZnO‐Reinforced 3D‐Bioprinted Scaffolds and Electrospun PVA‐Methotrexate Nanofibers

open access: yesMacromolecular Materials and Engineering, Volume 311, Issue 7, July 2026.
Green‐synthesized ZnO‐reinforced 3D‐printed scaffolds and electrospun PVA‐methotrexate nanofibers are combined into a bilayer wound dressing. The resulting system provides mechanical support, antibacterial performance, sustained methotrexate release, and cytocompatibility, offering a promising multifunctional strategy for localized wound management ...
Ahmad Saqib Qaeym   +6 more
wiley   +1 more source

Retinoic Acid Signalling Regulates Zebrafish Tooth Germ Repair Following Injury

open access: yesCell Proliferation, Volume 59, Issue 7, July 2026.
Retinoic acid signalling may regulate the repair processes in a tooth germ injury model using Tg(scpp5:Dendra2‐NTR) zebrafish and the nitroreductase (NTR)/metronidazole (MTZ) system. ABSTRACT Although the role of retinoic acid (RA) signalling in odontogenesis is well established, its involvement in the repair of injured tooth germs remains unclear.
Qiqi Liu   +4 more
wiley   +1 more source

Unveiling axolotl transcriptome for tissue regeneration with high-resolution annotation via long-read sequencing

open access: yesComputational and Structural Biotechnology Journal
Axolotls are known for their remarkable regeneration ability. Exploring their transcriptome provides insight into regenerative mechanisms. However, the current annotation of the axolotl transcriptome is limited, leaving the role of unannotated ...
Tian Qin   +7 more
doaj   +1 more source

Differential Immune Responses Correlate With Chytridiomycosis Severity in Italian Crested Newts

open access: yesMolecular Ecology, Volume 35, Issue 13, July 2026.
ABSTRACT In the midst of the current biodiversity crisis, amphibians are severely threatened by emerging diseases such as chytridiomycosis. Characterizing the mechanisms that underlie susceptibility to this disease is fundamental to improve amphibian conservation.
Léa Fieschi‐Méric   +7 more
wiley   +1 more source

Accelerated cell divisions drive the outgrowth of the regenerating spinal cord in axolotls

open access: yeseLife, 2016
Axolotls are unique in their ability to regenerate the spinal cord. However, the mechanisms that underlie this phenomenon remain poorly understood. Previously, we showed that regenerating stem cells in the axolotl spinal cord revert to a molecular state ...
Fabian Rost   +6 more
doaj   +1 more source

Functional Characterization of the Lin28/let-7 Circuit During Forelimb Regeneration in Ambystoma mexicanum and Its Influence on Metabolic Reprogramming

open access: yesFrontiers in Cell and Developmental Biology, 2020
The axolotl (Ambystoma mexicanum) is a caudate amphibian, which has an extraordinary ability to restore a wide variety of damaged structures by a process denominated epimorphosis.
Hugo Varela-Rodríguez   +9 more
doaj   +1 more source

Regeneration of the lizard heart after cryoinjury

open access: yesExperimental Physiology, Volume 111, Issue 7, Page 3310-3321, 1 July 2026.
Abstract Lizards are renowned for their tremendous potential to heal tissues and organs after injury, but little is known about myocardial regeneration in reptiles generally. Here, we study cardiac regeneration in the leopard gecko (Eublepharis macularius) to fill the knowledge gap between traditional models of poikilothermic (zebrafish) and ...
Martina Gregorovicova   +5 more
wiley   +1 more source

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