An approach for elucidating dermal fibroblast dedifferentiation in amphibian limb regeneration [PDF]
Zoological Letters, 2022 Urodele amphibians, Pleurodeles waltl and Ambystoma mexicanum, have organ-level regeneration capability, such as limb regeneration. Multipotent cells are induced by an endogenous mechanism in amphibian limb regeneration.
Akira Satoh +7 more
doaj +2 more sources
Regeneration inducers in limb regeneration [PDF]
Development Growth and Differentiation, 2015 Limb regeneration ability, which can be observed in amphibians, has been investigated as a representative phenomenon of organ regeneration. Recently, an alternative experimental system called the accessory limb model was developed to investigate early regulation of amphibian limb regeneration.
Akira Satoh
exaly +3 more sources
Unravelling the limb regeneration mechanisms of Polypedates maculatus, a sub-tropical frog, by transcriptomics [PDF]
BMC Genomics, 2023 Background Regeneration studies help to understand the strategies that replace a lost or damaged organ and provide insights into approaches followed in regenerative medicine and engineering.
Cuckoo Mahapatra +3 more
doaj +2 more sources
Different Requirement for Wnt/β-Catenin Signaling in Limb Regeneration of Larval and Adult Xenopus [PDF]
PLoS ONE, 2011 BACKGROUND:In limb regeneration of amphibians, the early steps leading to blastema formation are critical for the success of regeneration, and the initiation of regeneration in an adult limb requires the presence of nerves.
Haruki Ochi, Koji Tamura, Shiro Ohgo
exaly +2 more sources
The cellular logic of limb regeneration. [PDF]
ElifeHierarchical communication between cells with distinct positional memories orchestrates the regeneration of missing limb structures in axolotls.
Cherubino M, McCusker CD.
europepmc +3 more sources
Development of a ZRS Reporter System for the Newt (Cynops pyrrhogaster) During Terrestrial Limb Regeneration [PDF]
BiomedicinesBackground: Newts, a type of urodele amphibian, offer remarkable insights into regenerative medicine due to their extraordinary tissue regeneration capabilities—a challenging feat in humans.
Martin Miguel Casco-Robles +3 more
doaj +2 more sources
Limb Regeneration in Axolotl: Is It Superhealing? [PDF]
Scientific World Journal, The, 2006 The ability of axolotls to regenerate their limbs is almost legendary. In fact, urodeles such as the axolotl are the only vertebrates that can regenerate multiple structures like their limbs, jaws, tail, spinal cord, and skin (the list goes on) throughout their lives.
Stéphane Roy +2 more
exaly +4 more sources
Altered developmental programs and oriented cell divisions lead to bulky bones during salamander limb regeneration [PDF]
Nature Communications, 2022 Normal limb development relies on synchronized formation of cartilage and bone. Here, the authors show that in salamander limb regeneration these processes are decoupled: ossification occurs after the final size of regenerating cartilage is reached ...
Marketa Kaucka +19 more
doaj +2 more sources
Limb Regeneration inXenopus laevisFroglet
Scientific World Journal, The, 2006 Limb regeneration in amphibians is a representative process of epimorphosis. This type of organ regeneration, in which a mass of undifferentiated cells referred to as the “blastema” proliferate to restore the lost part of the amputated organ, is distinct
Akira Satoh, Koji Tamura
exaly +2 more sources
Muscles are barely required for the patterning and cell dynamics in axolotl limb regeneration [PDF]
Frontiers in Genetics, 2022 Regeneration of a complex appendage structure such as limb requires upstream and downstream coordination of multiple types of cells. Given type of cell may sit at higher upstream position to control the activities of other cells.
Yan Hu +11 more
doaj +2 more sources