Results 31 to 40 of about 48,368 (252)
Fishes, 2022 Wnt genes encode a family of secretory glycoproteins that are involved in various stages of organ development through regulation of cell proliferation, differentiation, and growth.
Yuanyuan Fu +5 more
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Toeing the line between regeneration and fibrosis
Frontiers in Cell and Developmental Biology, 2023 Understanding the remarkable capacity of vertebrates to naturally regenerate injured body parts has great importance for potential translation into human therapeutic applications.
Vivian Jou +2 more
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Journal of Functional Morphology and Kinesiology, 2017 Previous studies indicated that Fibroblast Growth Factors (FGFs) are present during tail and early limb regeneration in lizards, but FGFs disappear in the limb that turns into a scar and does not regenerate at 25–40 days post-amputation.
Lorenzo Alibardi
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Comparative transcriptional profiling of the axolotl limb identifies a tripartite regeneration-specific gene program. [PDF]
PLoS ONE, 2013 Understanding how the limb blastema is established after the initial wound healing response is an important aspect of regeneration research. Here we performed parallel expression profile time courses of healing lateral wounds versus amputated limbs in ...
Dunja Knapp +13 more
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BMC Genomics, 2018 Background Tissue regeneration is widely distributed across the tree of life. Among vertebrates, salamanders possess an exceptional ability to regenerate amputated limbs and other complex structures.
Claudia M. Arenas Gómez +4 more
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Regeneration of the limb: opinions on the reality
Journal of Materials Science: Materials in Medicine, 2013 Whenever the topic of re-growing human limbs is posed for discussion, it is often argued that ‘if a newt can do it, then so can we’. This notion, albeit promising, is somewhat like watching a science-fiction film; the individual components are currently available but we are far from realizing the complete picture.
Eugene Yong-Shun, See +2 more
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Comparative Analysis of Cartilage Marker Gene Expression Patterns during Axolotl and Xenopus Limb Regeneration. [PDF]
PLoS ONE, 2015 Axolotls (Ambystoma mexicanum) can completely regenerate lost limbs, whereas Xenopus laevis frogs cannot. During limb regeneration, a blastema is first formed at the amputation plane.
Kazumasa Mitogawa +3 more
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Regeneration of limb joints in the axolotl (Ambystoma mexicanum). [PDF]
PLoS ONE, 2012 In spite of numerous investigations of regenerating salamander limbs, little attention has been paid to the details of how joints are reformed. An understanding of the process and mechanisms of joint regeneration in this model system for tetrapod limb ...
Jangwoo Lee, David M Gardiner
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Limb Development and Regeneration [PDF]
American Zoologist, 1987 Experiments on developing and regenerating vertebrate limbs have led to the idea that pattern formation and growth control are causally linked. The mechanism by which position-specific growth occurs is termed intercalation, and evidence is presented that implicates intercalation in the initiation, maintenance and cessation of growth during limb ...
SUSAN V. BRYANT +2 more
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Deer antler renewal gives insights into mammalian epimorphic regeneration
Cell Regeneration, 2023 Deer antlers are the only known mammalian organ that, once lost, can fully grow back naturally. Hence, the antler offers a unique opportunity to learn how nature has solved the problem of mammalian epimorphic regeneration (EpR). Comprehensive comparisons
Chunyi Li
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