Results 101 to 110 of about 585,667 (306)

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

Advanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su, Guang Li, Yudong Guan, Qi Tian, Youzhi Qi, Yanqiu Zhang, Wenqian Wei, Xinxin Duan, Jiaxin Rui, Hongyan Zhu, Zengping Lin, Changchuan Xie, Zheni Xu, Yaying Wu, Xin Peng, Zhenjie Wang, Kun Chen, Xiaoyan Xin, Bing Zhang   +18 more
wiley   +1 more source

Toward a Rational Design of Conjugated Copolymers with Oxygenated Side Chains for Boosting Thermoelectric Properties

Advanced Energy Materials, EarlyView.
The molecular design strategy that integrates both side chain and backbone engineering in diketopyrrolopyrrole‐based conjugated polymers to identify the optimal balance between doping efficiency and microstructural order is demonstrated. Comprehensive spectroscopic, electrochemical, morphological, and structural characterizations reveal that the ...
Taewoong Han, Suhui Sim, Hoimin Kim, Taewoong Yoon, Hyungju Ahn, Seungjoo Chang, Namgyu Park, Hajeong Kim, Shabaz Alam, Dongki Lee, Sungjun Park, Sungjoo Lee, Jaewon Lee, Boseok Kang   +13 more
wiley   +1 more source

Taking sides or bridging worlds? Managerial responses to conflicts and tensions between the core operations and the administration in healthcare

BMC Health Services Research
Background Swedish public healthcare is increasingly characterised by a growing administrative layer and complex governance structures. While administrative personnel have grown in numbers, their coordination and integration with core clinical operations
Ingrid Svensson
doaj   +1 more source

Effect of various processing parameters on the quality of papaya fruit tea [PDF]

, 2005
Exotic fruits from which drinks are ma de in most tropical countries are so abundant and such in a great variety, that it would probably be impossible for people to sample all of them, but they worth a try.
Abdul Majid, Fadzilah Adibah, Md. Zaki, Nurul Asyikin, Muhammad, Ida Idayu   +2 more
core  

Climate Change Mitigation in the Dairy Sector: Uncovering Heterogeneity Through Eco‐Efficiency Clubs

Agribusiness, EarlyView.
ABSTRACT Combining climate change goals with economic targets is crucial for the dairy sector, which is a significant contributor to agricultural greenhouse gas (GHG) emissions worldwide. In this paper, we assess economic and climate change implications of dairy production with panel data of Irish dairy farms from 2013 to 2021.
Doris Läpple, Christian Stetter, Cathal Buckley   +2 more
wiley   +1 more source

Basic research on pinching cultivation to reduce lodging damage and increase yield of Japanese okra (Abelmoschus esculentus L.)

Heliyon
The main okra (Abelmoschus esculentus L.) production areas in Japan are located in the warm southwestern region. The harvest period for Japanese okra includes the rainy and typhoon seasons.
Lime Sato, Mona Futami, Satoru Motoki
doaj   +1 more source

Which Method Best Predicts Postoperative Complications: Deep Learning, Machine Learning, or Conventional Logistic Regression?

Annals of Gastroenterological Surgery, EarlyView.
Deep learning has shown promise in predicting postoperative complications, particularly when using image or time‐series data. However, on tabular clinical data such as the NCD, it often underperforms compared to conventional machine learning. Integrating multimodal data may enhance predictive accuracy and interpretability in surgical care.
Ryosuke Fukuyo, Masanori Tokunaga, Hiroyuki Yamamoto, Hideki Ueno, Yusuke Kinugasa   +4 more
wiley   +1 more source

The impact of superphosphate and surface-applied lime on the profitability and sustainability of wool production on the tablelands of NSW [PDF]

Soil acidification is one of the major forms of soil degradation in higher rainfall areas of the tablelands of NSW. A grazing experiment was conducted near Sutton, NSW, to assess the effect of various rates of superphosphate, lime, sewage ash and ...
Armstrong, P., Brassil, T., Garden, P., Graham, Phil, Khairo, Salahadin A., Langford, Colin, Norton, Mark R.   +6 more
core   +1 more source

Feature Selection for Machine Learning‐Driven Accelerated Discovery and Optimization in Emerging Photovoltaics: A Review

Advanced Intelligent Discovery, EarlyView.
Feature selection combined with machine learning and high‐throughput experimentation enables efficient handling of high‐dimensional datasets in emerging photovoltaics. This approach accelerates material discovery, improves process optimization, and strengthens stability prediction, while overcoming challenges in data quality and model scalability to ...
Jiyun Zhang, Jiayi Tan, Qizhen Song, Tian Du, Jens Hauch, Christoph J. Brabec   +5 more
wiley   +1 more source

In vitro antimicrobial activity of musk lime, key lime and lemon extracts against food related pathogenic and spoilage bacteria [PDF]

, 2014
The demand for novel antimicrobial agents from natural resources has been increased worldwide for food conservation purpose. In this study antimicrobial activity of musk lime, key lime and lemon were evaluated against various food borne pathogens and ...
Abu Bakar, Fatimah, Mahyudin, Nor Ainy, Saari, Nazamid, Velu, Selvi, Zaman, Muhammad Zukhrufuz   +4 more
core