Results 81 to 90 of about 209,133 (315)

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Probabilistic Slope Stability Analysis: A Case Study

open access: yesSakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2018
Probabilistic slope stabilityanalyses are becoming more and more popular to evaluate the safety level ofslopes and the associated risk and reliability, especially in the recent years.Probabilistic approach can take into account the uncertainties and ...
Nejan Huvaj, Emir Ahmet Oğuz
doaj   +1 more source

Equilibrium pressure limits in stellarators

open access: yes, 2023
This thesis delves into the potential of magnetic fusion energy, and in particular focuses on the stellarator concept. Stellarators use external coils to produce 3-dimensional (3D) magnetic fields that confine a thermonuclear plasma in a topologically toroidal volume, and thus do not, in general, require an externally driven plasma current. This is one
openaire   +1 more source

Limit properties of Bertrand equilibria with exogenous entry [PDF]

open access: yes
For a large class of demand and cost functions, we characterize the limit equilibrium set under Bertrand oligopoly when entry is exogenous. Unless average cost is constant, we find that the folk theorem of perfect competition necessarily fails.
Prabal Roy Chowdhury
core  

Equilibrium in a market with intermediation is Walrasian [PDF]

open access: yes, 1994
We show that a profit maximizing monopolistic intermediary may behave approximately like a Walrasian auctioneer setting bid and ask prices nearly equal to Walrasian equilibrium prices.
Wooders, John
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Cournot-Walras equilibrium as a subgame perfect equilibrium [PDF]

open access: yes
In this paper, we investigate the problem of the strategic foundation of the Cournot-Walras equilibrium approach. To this end, we respecify à la Cournot-Walras the mixed version of a model of simultaneous, noncooperative exchange, originally proposed by
Busetto, Francesca   +2 more
core  

NOVEL NUMERICAL PROCEDURES FOR LIMIT ANALYSIS OF STRUCTURES: MESH-FREE METHODS AND MATHEMATICAL PROGRAMMING [PDF]

open access: yes, 2010
Current research in the field of limit analysis is focussing on the development of numerical tools which are sufficiently efficient and robust to be used in engineering practice.
Le, Canh
core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

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