Results 51 to 60 of about 166,389,856 (245)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Método para a determinação de hexazinone e tebutiuron em água Method for determination of hexazinone and tebuthiuron in water

Química Nova, 2005
This work presents an alternative method for determination of the herbicides tebuthiuron and hexazinone in ground water. The extraction was made with dichloromethane and the analyses by high performance liquid chromatography (HPLC), using reversed-phase ...
Vera L. Ferracini, Sonia C. N. Queiroz, Marco A. F. Gomes, Gustavo L. Santos   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Detection and Quantification Limits for Polyethylene Particles Combining the Thermal Rock-Eval^® Method with a Mathematical Extrapolation Procedure

Microplastics
The main aim of this work is to define the limits of detection (LOD) and quantification (LOQ) for polyethylene (PE) particles using a pyrolysis and oxidation-based method, the thermal Rock-Eval® device, combined with a mathematical extrapolation ...
Maria-Fernanda Romero-Sarmiento, Daniela Bauer, Sébastien Rohais   +2 more
doaj   +1 more source

Analyzing siRNA Concentration, Complexation and Stability in Cationic Dendriplexes by Stem-Loop Reverse Transcription-qPCR

Pharmaceutics, 2022
RNA interference (RNAi) is a powerful therapeutic approach for messenger RNA (mRNA) level regulation in human cells. RNAi can be triggered by small interfering RNAs (siRNAs) which are delivered by non-viral carriers, e.g., dendriplexes.
Maximilian Neugebauer, Clara E. Grundmann, Michael Lehnert, Felix von Stetten, Susanna M. Früh, Regine Süss   +5 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Pour une sociologie historique de la quantification

, 2008
La quantification est devenue un signe d’objectivité, de rigueur et d’impartialité mobilisée dans des situations très variées, depuis le débat politique jusqu’à la démonstration scientifique, en passant par les indicateurs d’entreprise ou la mesure de l ...
Alain Desrosières
core   +1 more source

Modernization Data Analysis and Visualization for Food Safety Research Outcomes

Applied Sciences
Appropriate data collection and using reliable and accurate procedures are the first steps in conducting an experiment that will provide trustworthy outcomes.
David A. Vargas, Rossy Bueno López, Diego E. Casas, Andrea M. Osorio-Doblado, Karla M. Rodríguez, Nathaly Vargas, Sara E. Gragg, Mindy M. Brashears, Markus F. Miller, Marcos X. Sanchez-Plata   +9 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source