Results 141 to 150 of about 36,479 (161)
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European Food Research and Technology, 2008
The predominant approach for quantification of genetically modified organisms (GMO) is the application of quantitative real-time PCR. However, for a large number of processed food and feed products, this approach is unsuitable, because they contain low amounts (mass) of amplifiable DNA. Here we present a novel approach, “Single molecule quantification”
Knut G. Berdal +3 more
openaire +3 more sources
The predominant approach for quantification of genetically modified organisms (GMO) is the application of quantitative real-time PCR. However, for a large number of processed food and feed products, this approach is unsuitable, because they contain low amounts (mass) of amplifiable DNA. Here we present a novel approach, “Single molecule quantification”
Knut G. Berdal +3 more
openaire +3 more sources
2021
Optical methods (light or electron microscopy) are, in most cases, the basis for measuring the asbestos concentration either in air or in materials. The individual methods are described in a variety of guidelines or standards. The definition of terms like detection limit and analytical sensitivity have led to numerous discussions, driven by the fact ...
openaire +3 more sources
Optical methods (light or electron microscopy) are, in most cases, the basis for measuring the asbestos concentration either in air or in materials. The individual methods are described in a variety of guidelines or standards. The definition of terms like detection limit and analytical sensitivity have led to numerous discussions, driven by the fact ...
openaire +3 more sources
Supercharging reagents in LC-MS/MS hormone analyses: Enhancing ionization, not limit of quantification [PDF]
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2022 One of the critical steps during LC-MS/MS hormone analyses that affects the sensitivity of the assay is the ionization process. Enhancing ionization efficiencies by the addition of supercharging reagents might be one way to improve sensitivity and reduce
Annemieke C Heijboer +2 more
exaly +2 more sources
Are LOD and LOQ Reliable Parameters for Sensitivity Evaluation of Spectroscopic Methods?
Journal of AOAC INTERNATIONAL, 2018 The limit of detection (LOD) and the limit of quantification (LOQ) are common parameters to assess the sensitivity of analytical methods. In this study, the LOD and LOQ of previously reported terbium sensitized analysis methods were calculated by ...
Ali Shayanfar, Shayanfar Ali
exaly +2 more sources
Handling Data Below the Limit of Quantification in Mixed Effect Models
AAPS Journal, 2009 The purpose of this study is to investigate the impact of observations below the limit of quantification (BQL) occurring in three distinctly different ways and assess the best method for prevention of bias in parameter estimates and for illustrating ...
Martin Bergstrand +2 more
exaly +2 more sources
Likelihood based approaches to handling data below the quantification limit using NONMEM VI
Journal of Pharmacokinetics and Pharmacodynamics, 2008 PURPOSE: To evaluate the likelihood-based methods for handling data below the quantification limit (BQL) using new features in NONMEM VI. METHODS: A two-compartment pharmacokinetic model with first-order absorption was chosen for investigation.
Mats O Karlsson +2 more
exaly +2 more sources