Results 101 to 110 of about 1,272,092 (238)

Le retour d'expérience [PDF]

open access: yes, 1992
Dans l'avant propos de l'Archipel du danger, G.Y. Kervern et P. Rubise écrivent que "depuis le tremblement de terre de Lisbonne en 1755 et la polémique qui s'ensuit entre Voltaire et Rousseau sur la place de l'homme et de Dieu dans les catastrophes, l ...
Pineau, Jean-Philippe   +2 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Limites ao princípio da reparação integral no direito brasileiro

open access: yesCivilistica.com, 2018
O presente artigo tem por objetivo investigar o princípio da reparação integral no ordenamento jurídico brasileiro. Analisa-se sua trajetória, seu fundamento constitucional e natureza principiológica.
Carlos Edison do Rêgo Monteiro Filho
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Vicinalidade e parentesco: limites, categorias e práticas [PDF]

open access: yes, 2007
Processos judiciais recorrentes envolvendo vários arguidos aparentados entre si, assim como a reclusão conjunta de vários familiares, são fenómenos recentes que ganharam expressão em Portugal a propósito do tráfico de droga e de outras actividades ...
Cunha, Manuela Ivone P. da
core  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Les Organisations de la Société Civile et la Lutte Contre la Pauvreté en Afrique Subsaharienne [PDF]

open access: yes, 2004
The paper presents the role played by civil society organisations to bring down the ...
Aurélien C. Atidegla   +11 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Dialyse péritonéale chez l'enfant : Approches physiopathologiques, prescription et gestion des complications pour un traitement adéquat.

open access: yesBulletin de la Dialyse à Domicile
La dialyse péritonéale (DP) est la modalité de suppléance rénale la plus utilisée chez l’enfant dans le monde. Elle utilise la membrane péritonéale comme surface d’échange semi perméable pour les échanges d’eau et de solutés entre le dialysat et les ...
RoubaA Bechara   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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