Results 151 to 160 of about 2,942,734 (312)
Singapore Pte. Ltd. : A Question of Limits
, 2017 The notion of limits pertains specifically to Singapore’s physical size and resources, and how these limits are circumvented, even celebrated, through the nation’s capacities, ambitions, projections and influences.
Lau, C.
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
THE EFFECTS OF MINIMUM SIZE LIMITS ON RECREATIONAL FISHING [PDF]
Minimum size limits have become an increasingly popular management tool in recreational fisheries. This popularity stems from the potential of minimum size limits to accomplish the twin goals of limiting overfishing and improving fishing quality through ...
Ruliffson, Jane A., Homans, Frances R.
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FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Political Campaign Spending Limits [PDF]
Political campaign spending ceilings are purported to limit the incumbent’s ability to exploit his fundraising advantage. If the challenger does not have superior campaign effectiveness, in contrast to conventional wisdom, we show that the incumbent ...
Tuvana Pastine, Ivan Pastine
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Tax Limits, Houses, and Schools: Seemingly Unrelated and Offsetting Effects [PDF]
Property tax limitations, as well as other tax and expenditure restrictions on state and local governments in the United States, date back to the late nineteenth century. A surge in property tax limitation legislation occurred in the late 1970s and early
Paul A. Coomes +2 more
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