Results 161 to 170 of about 2,942,734 (312)

On The Limits of Limits [PDF]

Microscopy Today, 2003
openaire   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Social Preferences and Transport Policy:The case of US speed limits [PDF]

This article, in reviewing the long-running US debate on speed limits, illustrates how a different valuation of the trade-off between private mobility needs and safety concerns can shape transport policies.
Daniel Albalate
core  

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The accuracy of VO2 max, heart rate and energy expenditure measurements from Google Pixel Watch 3. [PDF]

PLoS One
Lambe R, Schumann M, Hamilton S, Donnelly L, White T, O'Reilly S, Lally S, Doherty C.   +7 more
europepmc   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Front Cover Vol.16 No.1 2019

, 2019
Limits, Jurnal
core   +1 more source

Degrees-of-Freedom Approximations for Conditional-Mean Inference in Random-Lot Stability Analysis. [PDF]

Pharm Stat
Karl AT, Rushing H, Burdick RK, Hofer J.
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Erratum: Intramuscular plasmid DNA electroporation sequesters neoantigen-specific CD8⁺ T cells in treated muscle and limits tumor infiltration. [PDF]

Mol Ther Oncol
Bianchi A, Esposito M, Giacomelli T, Esposito I, Tonini C, Aurisicchio L, Palombo F.   +6 more
europepmc   +1 more source