Results 171 to 180 of about 2,942,734 (312)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Postural orthostatic tachycardia syndrome in adolescents with ME/CFS - a case control study. [PDF]

Front Pediatr
Leone A, Gerrer K, Viereck A, Grabbe A, Kircher A, Behrends U, Maier A.   +6 more
europepmc   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

A preliminary investigation of welfare migration induced by time limits [PDF]

Studies on welfare programs in the United States have identified three types of welfare migration (employment, benefit, and amenity-related). This paper introduces a fourth type of migration induced by welfare time limits.
Snarr, Hal W., Burkey, Mark L.
core  

Understanding the Limits of Patient Safety Classification Systems for Health Information Technology-Related Incidents. [PDF]

JMIR Hum Factors
Jabin MSR.
europepmc   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Multivariate control charts based on Mahalanobis distance for bivariate quality monitoring in petrochemical and pharmaceutical analyses. [PDF]

Anal Bioanal Chem
Ijiri JS, Gonzales PV, Lourenço FR, de Oliveira EC.   +3 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Beyond the limits: silent majority

, 2004
Solo show (Tabrizian retrospective) premiering two closely related photographic projects inspired by Baudrillard and focusing on corporate culture: the series Beyond the Limits (8 images of which 5 submitted to RAE 2008), and Silent Majority (1 large ...
Tabrizian, M.
core  

ESHRE position paper: international limits on the number of offspring per gamete donor. [PDF]

Hum Reprod
Frith L, Tassot J, Ahlstrom A, Baldani DP, Calhaz-Jorge C, Nikolov G, Thorn P, Vermeulen N, Kirkman-Brown J.   +8 more
europepmc   +1 more source