Results 161 to 170 of about 6,528,865 (246)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Elemental Analysis of Maha Kumbh-2025 Water Along With Intercomparison With Other Water Resources Using Synchrotron-Assisted Total-Reflection X-Ray Fluorescence Analysis: A Case Study. [PDF]

Water Environ Res
Tiwari MK, Khooha A, Trivedi A, Potey GG, Mahadik VK, Singh AK.   +5 more
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Reliability of Auditory-Perceptual Analysis in the Study of Speech Function in Patients with Unilateral Cleft and Palate. [PDF]

J Clin Med
Bloeck A, Doyle NA, Bartel S, Krimmel M.
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Aflatoxin levels in dried figs export from Turkey. [PDF]

Mycotoxin Res
Yarali E, Ulken U, Pehlivan R.
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Comparison of Reproducibility and Repeatability of Corneal Topography Measured by ATLAS 500 and ATLAS 9000 in Average Patient Population. [PDF]

Clin Ophthalmol
Tañá-Rivero P, Orts-Vila P, Tañá-Sanz P, Tañá-Sanz S, Ramos M, Tello-Elordi C.   +5 more
europepmc   +1 more source

Os limites do limite

Teresa, 2003
openaire   +2 more sources