Results 1 to 10 of about 4,813,932 (329)

SLFN11 Restricts LINE-1 Mobility [PDF]

open access: yesCells
Long interspersed element-1 (LINE-1) is the only active autonomous transposon comprising about 17% of human genomes. LINE-1 transposition can cause the mutation and rearrangement of the host’s genomic DNA.
Zhongjie Ye   +13 more
doaj   +3 more sources

Onsite Identification of Air Pollutants in Plastic Sports-Field Using Portable Gas ChromatographyMass Spectrometry via Drone-Based Solid-Phase Microextraction Sampling [PDF]

open access: yesZhipu Xuebao, 2023
Plastic sports-fields are commonly used in communities, schools and other public places nowadays, which can offer positive benefits to fitness and sports. Plastic sports-fields are usually made of petroleum-based materials. Under high-temperature weather,
MO Wen-zheng1   +7 more
doaj   +1 more source

Anthropometric, biochemical, and haematological indicators associated with hyperhomocysteinemia and their relation to global DNA methylation in a young adult population

open access: yesEpigenetics, 2022
Increased homocysteine (Hcy) levels have been associated with a higher risk of cardiovascular and neurodegenerative diseases. Passive DNA demethylation has been suggested as one of the mechanisms implicated in the development of these conditions, and ...
Fernanda Hernandez-Landero   +5 more
doaj   +1 more source

Genome-wide DNA hypermethylation and homocysteine increase a risk for myopia [PDF]

open access: yesInternational Journal of Ophthalmology, 2019
AIM: To test for the association between genome-wide methylation and myopia in human and mice. METHODS: Long interspersed nucleotide element 1 (LINE-1) methylation levels were used to surrogate genome-wide methylation level.
Edward Hsi   +5 more
doaj   +1 more source

LINE-1 Expression is Associated with the Effectiveness of EGFR Inhibitors in Colorectal Cancer Cells

open access: yesTokyo Women's Medical University Journal, 2020
Background: Colorectal cancer (CRC) sidedness is predictive of anti-epidermal growth factor receptor (anti-EGFR) antibody therapy effectiveness; however, the mechanism linking them is unclear.
Eiichiro Yamamoto   +5 more
doaj   +1 more source

Electrophilic-nucleophilic properties as a factor in the formation of antifriction and hydrophobic properties of surface-modified metals with ammonium and organosilicon compounds

open access: yesКонденсированные среды и межфазные границы, 2021
Stabilisation of the functional properties of dispersed and compact metals, as well as the regulation of their reactivity, improvement of water-repellent, antifriction and anti-corrosion properties by creating the protective films on the surface is an ...
Andrey G. Syrkov   +3 more
doaj   +1 more source

Retrotransposon-induced mosaicism in the neural genome [PDF]

open access: yesOpen Biology, 2018
Over the past decade, major discoveries in retrotransposon biology have depicted the neural genome as a dynamic structure during life. In particular, the retrotransposon LINE-1 (L1) has been shown to be transcribed and mobilized in the brain ...
Gabriela O. Bodea   +2 more
doaj   +1 more source

Methylation profiles of global LINE-1 DNA and the GSTP1 promoter region in children exposed to lead (Pb)

open access: yesEpigenetics, 2022
Lead (Pb) exposure has adverse health effects and altered DNA methylation may contribute to Pb toxicity. LINE-1 is an interspersed repeated DNA that is used as a surrogate marker for estimating genomic DNA methylation levels, and GSTP1 is an isozyme that
Yared Beyene Yohannes   +10 more
doaj   +1 more source

Evaluating the Downstream Development Strategy of Oil Companies: The Case of Rosneft

open access: yesResources, 2022
The relevance of this study is due to the low rate of development of the downstream sectors of Russian oil companies. Against a background of the sale of significant volumes of oil and gas raw materials, Russia lags behind world leaders in the production
Oksana Marinina   +4 more
doaj   +1 more source

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