Results 11 to 20 of about 28,196,398 (315)
SLFN11 Restricts LINE-1 Mobility [PDF]
CellsLong interspersed element-1 (LINE-1) is the only active autonomous transposon comprising about 17% of human genomes. LINE-1 transposition can cause the mutation and rearrangement of the host’s genomic DNA.
Zhongjie Ye +13 more
doaj +4 more sources
Onsite Identification of Air Pollutants in Plastic Sports-Field Using Portable Gas ChromatographyMass Spectrometry via Drone-Based Solid-Phase Microextraction Sampling [PDF]
Zhipu Xuebao, 2023 Plastic sports-fields are commonly used in communities, schools and other public places nowadays, which can offer positive benefits to fitness and sports. Plastic sports-fields are usually made of petroleum-based materials. Under high-temperature weather,
MO Wen-zheng1 +7 more
doaj +1 more source
The Evolution of Line-1 in Vertebrates [PDF]
Genome Biology and Evolution, 2016 The abundance and diversity of the LINE-1 (L1) retrotransposon differ greatly among vertebrates. Mammalian genomes contain hundreds of thousands L1s that have accumulated since the origin of mammals. A single group of very similar elements is active at a time in mammals, thus a single lineage of active families has evolved in this group.
Boissinot, Stéphane, Sookdeo, Akash
openaire +2 more sources
Regulation of LINE-1 in mammals [PDF]
Biomolecular Concepts, 2014 Abstract Transposable elements (TEs) are mobile DNA elements that represent almost half of the human genome. Transposition of TEs has been implicated as a source of genome evolution and acquisition of new traits but also as an origin of diseases.
Bodak, Maxime +2 more
openaire +5 more sources
Genome-wide DNA hypermethylation and homocysteine increase a risk for myopia [PDF]
International Journal of Ophthalmology, 2019 AIM: To test for the association between genome-wide methylation and myopia in human and mice. METHODS: Long interspersed nucleotide element 1 (LINE-1) methylation levels were used to surrogate genome-wide methylation level.
Edward Hsi +5 more
doaj +1 more source
Epigenetics, 2022 Increased homocysteine (Hcy) levels have been associated with a higher risk of cardiovascular and neurodegenerative diseases. Passive DNA demethylation has been suggested as one of the mechanisms implicated in the development of these conditions, and ...
Fernanda Hernandez-Landero +5 more
doaj +1 more source
Конденсированные среды и межфазные границы, 2021 Stabilisation of the functional properties of dispersed and compact metals, as well as the regulation of their reactivity, improvement of water-repellent, antifriction and anti-corrosion properties by creating the protective films on the surface is an ...
Andrey G. Syrkov +3 more
doaj +1 more source
Epigenetics, 2022 Lead (Pb) exposure has adverse health effects and altered DNA methylation may contribute to Pb toxicity. LINE-1 is an interspersed repeated DNA that is used as a surrogate marker for estimating genomic DNA methylation levels, and GSTP1 is an isozyme that
Yared Beyene Yohannes +10 more
doaj +1 more source
LINE-1 Expression is Associated with the Effectiveness of EGFR Inhibitors in Colorectal Cancer Cells
Tokyo Women's Medical University Journal, 2020 Background: Colorectal cancer (CRC) sidedness is predictive of anti-epidermal growth factor receptor (anti-EGFR) antibody therapy effectiveness; however, the mechanism linking them is unclear.
Eiichiro Yamamoto +5 more
doaj +1 more source
Retrotransposon-induced mosaicism in the neural genome [PDF]
Open Biology, 2018 Over the past decade, major discoveries in retrotransposon biology have depicted the neural genome as a dynamic structure during life. In particular, the retrotransposon LINE-1 (L1) has been shown to be transcribed and mobilized in the brain ...
Gabriela O. Bodea +2 more
doaj +1 more source