Results 31 to 40 of about 28,196,398 (315)

ADAR1 restricts LINE-1 retrotransposition [PDF]

Nucleic Acids Research, 2016
Adenosine deaminases acting on RNA (ADARs) are involved in RNA editing that converts adenosines to inosines in double-stranded RNAs. ADAR1 was demonstrated to be functional on different viruses exerting either antiviral or proviral effects. Concerning HIV-1, several studies showed that ADAR1 favors viral replication.
Orecchini, Elisa, Doria, Margherita, Antonioni, Ambra, Galardi, Silvia, Ciafré, Silvia Anna, Frassinelli, Loredana, MANCONE, Carmine, Montaldo, Claudia, TRIPODI, Marco, Michienzi, Alessandro   +9 more
openaire   +3 more sources

Magnetic Resonance Compatibility Analysis Method of Surgical Robotic System Based on Image Quality Evaluation

Chinese Journal of Magnetic Resonance, 2023
To ensure the safety and precision of surgery, the robotic system applied in magnetic resonance (MR) image-guided robot-assisted surgery should be MR-compatible. In terms of this issue, a MR compatibility analysis method for surgical robotic system based
LI Pan, FANG Delei, ZHANG Junxia, MA Debei   +3 more
doaj   +1 more source

LINE-1 methylation status in prostate cancer and non-neoplastic tissue adjacent to tumor in association with mortality

Epigenetics, 2017
Aberrant DNA methylation seems to be associated with prostate cancer behavior. We investigated LINE-1 methylation in prostate cancer and non-neoplastic tissue adjacent to tumor (NTAT) in association with mortality from prostate cancer.
Valentina Fiano, Daniela Zugna, Chiara Grasso, Morena Trevisan, Luisa Delsedime, Luca Molinaro, Anna Gillio-Tos, Franco Merletti, Lorenzo Richiardi   +8 more
doaj   +1 more source

Study of the Pipeline in Emergency Operation and Assessing the Magnitude of the Gas Leak

Energies, 2022
Accidents on gas pipelines cause significant damage to the national economy and the economy of the state. Thus, it is necessary to always be prepared for such situations in order to restore the normal operation of the gas pipeline as soon as possible. An
Andrey Schipachev, Vadim Fetisov, Ayrat Nazyrov, Lee Donghee, Abdurakhmat Khamrakulov   +4 more
doaj   +1 more source

Decoupling of DNA methylation and activity of intergenic LINE-1 promoters in colorectal cancer

Epigenetics, 2017
Hypomethylation of LINE-1 repeats in cancer has been proposed as the main mechanism behind their activation; this assumption, however, was based on findings from early studies that were biased toward young and transpositionally active elements.
Natasha Vafadar-Isfahani, Christina Parr, Lara E. McMillan, Juliane Sanner, Zhao Yeo, Stephen Saddington, Oliver Peacock, Hazel A. Cruickshanks, Richard R. Meehan, Jonathan N. Lund, Cristina Tufarelli   +10 more
doaj   +1 more source

Periprocedural Risk Predictors Affecting Long-Term Prognosis in Patients With Chronic Obstructive Pulmonary Disease Undergoing Coronary Artery Bypass Grafting [PDF]

Texas Heart Institute Journal
Objective This study sought to identify periprocedural risk predictors that affect long-term prognosis in patients with chronic obstructive pulmonary disease (COPD) undergoing isolated coronary artery bypass grafting (CABG). Methods All consecutive 4,871
Aleksander Dokollari, MD, PhD, Serge Sicouri, MD, Leila Hosseinian, MD, Ozgun Erten, MD, Basel Ramlawi, MD, Gianluigi Bisleri, MD, Massimo Bonacchi, MD, Noah Sicouri, MS, Gianluca Torregrossa, MD, MEBCTS, Francis P. Sutter, DO   +9 more
doaj   +1 more source

Adaptive Evolution in LINE-1 Retrotransposons [PDF]

Molecular Biology and Evolution, 2001
We traced the sequence evolution of the active lineage of LINE-1 (L1) retrotransposons over the last approximately 25 Myr of human evolution. Five major families (L1PA5, L1PA4, L1PA3B, L1PA2, and L1PA1) of elements have succeeded each other as a single lineage. We found that part of the first open-reading frame (ORFI) had a higher rate of nonsynonymous
S, Boissinot, A V, Furano
openaire   +2 more sources

Impact of Atrial Fibrillation Type on Outcomes of Transcatheter Aortic Valve Replacement for Aortic Stenosis: A Single-Center Analysis [PDF]

Texas Heart Institute Journal
Background: Atrial fibrillation (AF) is a recognized risk factor for mortality after transcatheter aortic valve replacement for severe aortic stenosis, but the impact of different types of AF on clinical outcomes remains unclear.
Yoshiyuki Yamashita, MD, PhD, Serge Sicouri, MD, Massimo Baudo, MD, Roberto Rodriguez, MD, Eric M. Gnall, DO, Paul M. Coady, MD, Harish Jarrett, MD, Sandra V. Abramson, MD, Katie M. Hawthorne, MD, Scott M. Goldman, MD, William A. Gray, MD, Basel Ramlawi, MD   +11 more
doaj   +1 more source

Approaches to Assessing the Strategic Sustainability of High-Risk Offshore Oil and Gas Projects

Journal of Marine Science and Engineering, 2020
In the face of today’s global challenges, oil and gas companies must define long-term priorities and opportunities in implementing complex Arctic offshore projects, taking into account environmental, economic, technological and social aspects.
Alexey Cherepovitsyn, Anna Tsvetkova, Nadejda Komendantova   +2 more
doaj   +1 more source

Inhibition of LINE-1 Retrotransposition by Capsaicin [PDF]

International Journal of Molecular Sciences, 2018
Long interspersed nuclear element 1 (LINE-1 or L1) is a non-long terminal repeat (LTR) retrotransposon that constitutes approximately 17% of the human genome. Since approximately 100 copies are still competent for retrotransposition to other genomic loci, dysregulated retrotransposition of L1 is considered to be a major risk factor of endogenous ...
Yuki Nishikawa, Ryota Nakayama, Shunsuke Obika, Eriko Ohsaki, Keiji Ueda, Tomoyuki Honda   +5 more
openaire   +2 more sources