Results 31 to 40 of about 4,929,883 (200)

The Evolution of Line-1 in Vertebrates [PDF]

Genome Biology and Evolution, 2016
The abundance and diversity of the LINE-1 (L1) retrotransposon differ greatly among vertebrates. Mammalian genomes contain hundreds of thousands L1s that have accumulated since the origin of mammals. A single group of very similar elements is active at a time in mammals, thus a single lineage of active families has evolved in this group.
Boissinot, Stéphane, Sookdeo, Akash
openaire   +2 more sources

Periprocedural Risk Predictors Affecting Long-Term Prognosis in Patients With Chronic Obstructive Pulmonary Disease Undergoing Coronary Artery Bypass Grafting [PDF]

Texas Heart Institute Journal
Objective This study sought to identify periprocedural risk predictors that affect long-term prognosis in patients with chronic obstructive pulmonary disease (COPD) undergoing isolated coronary artery bypass grafting (CABG). Methods All consecutive 4,871
Aleksander Dokollari, MD, PhD, Serge Sicouri, MD, Leila Hosseinian, MD, Ozgun Erten, MD, Basel Ramlawi, MD, Gianluigi Bisleri, MD, Massimo Bonacchi, MD, Noah Sicouri, MS, Gianluca Torregrossa, MD, MEBCTS, Francis P. Sutter, DO   +9 more
doaj   +1 more source

Impact of Atrial Fibrillation Type on Outcomes of Transcatheter Aortic Valve Replacement for Aortic Stenosis: A Single-Center Analysis [PDF]

Texas Heart Institute Journal
Background: Atrial fibrillation (AF) is a recognized risk factor for mortality after transcatheter aortic valve replacement for severe aortic stenosis, but the impact of different types of AF on clinical outcomes remains unclear.
Yoshiyuki Yamashita, MD, PhD, Serge Sicouri, MD, Massimo Baudo, MD, Roberto Rodriguez, MD, Eric M. Gnall, DO, Paul M. Coady, MD, Harish Jarrett, MD, Sandra V. Abramson, MD, Katie M. Hawthorne, MD, Scott M. Goldman, MD, William A. Gray, MD, Basel Ramlawi, MD   +11 more
doaj   +1 more source

Approaches to Assessing the Strategic Sustainability of High-Risk Offshore Oil and Gas Projects

Journal of Marine Science and Engineering, 2020
In the face of today’s global challenges, oil and gas companies must define long-term priorities and opportunities in implementing complex Arctic offshore projects, taking into account environmental, economic, technological and social aspects.
Alexey Cherepovitsyn, Anna Tsvetkova, Nadejda Komendantova   +2 more
doaj   +1 more source

Embryo culture in presence of oviductal fluid induces DNA methylation changes in bovine blastocysts [PDF]

, 2017
During the transit through the oviduct, the early embryo initiates an extensive DNA methylation reprogramming of its genome. Given that these epigenetic modifications are susceptible to environmental factors, components present in the oviductal milieu ...
Barrera, Antonio Daniel, Fonseca Balvís, Noelia, Garcia, Elina Vanesa, Gutiérrez Adan, Alfonso, Hamdi, Meriem, López Cardona, Ángela Patricia, Rizos, Dimitrios, Sánchez Calabuig, María Jesús   +7 more
core   +1 more source

Analysis of aberrantly methylated sequnces in circulating DNA from blood of patients with lung cancer [PDF]

, 2016
Malignant cell transformation is accompanied by two processes of DNA methylation changes: promoter hypermethylation of specific genes and hypomethylation of retrotransposons.
Бондарь, А. А., Добродеев, А. Ю., Пономарева, Анастасия Алексеевна   +2 more
core   +2 more sources

Epigenomic Diversity of Colorectal Cancer Indicated by LINE-1 Methylation in a Database of 869 Tumors [PDF]

, 2012
Background: Genome-wide DNA hypomethylation plays a role in genomic instability and carcinogenesis. LINE-1 (L1 retrotransposon) constitutes a substantial portion of the human genome, and LINE-1 methylation correlates with global DNA methylation status ...
Baba, Yoshifumi, Fuchs, Charles Stewart, Giovannucci, Edward L., Hazra, Aditi, Hunter, David J., Huttenhower, Curtis, Nosho, Katsuhiko, Ogino, Shuji, Schernhammer, Eva S, Shima, Kaori, Tanaka, Noriko   +10 more
core   +1 more source

Engineered LINE-1 retrotransposition in nondividing human neurons [PDF]

, 2016
Half the human genome is made of transposable elements (TEs), whose ongoing activity continues to impact our genome. LINE-1 (or L1) is an autonomous non-LTR retrotransposon in the human genome, comprising 17% of its genomic mass and containing an average
Amador-Cubero, Suyapa, Ayllon, Veronica, Benkaddour-Boumzaouad, Meriem, Blanco-Jimenez, Eva, Garcia-Castro, Javier, Garcia-Perez, Jose L., Goodier, John L., Heras, Sara R., Macia, Angela, Menendez, Pablo, Muotri, Alysson R., Muñoz-Lopez, Martin, Ng, Philip, Rubio, Alejandro, Sanchez, Laura, Widmann, Thomas J.   +15 more
core   +5 more sources

Crossing the LINE Toward Genomic Instability: LINE-1 Retrotransposition in Cancer [PDF]

, 2015
Retrotransposons are repetitive DNA sequences that are positioned throughout the human genome. Retrotransposons are capable of copying themselves and mobilizing new copies to novel genomic locations in a process called retrotransposition.
Jacqueline R. Kemp, Michelle S. Longworth   +1 more
core   +4 more sources

Improvement of slope soil consolidation capacity of plant root system based on regulation of root architecture

Rock and Soil Mechanics, 2021
The effect of plant slope protection is strongly associated with the root architecture in soil. In this paper, the water?fertilizer combination method was used to regulate the plant root configuration, and the influence of the regulated plant root ...
LI Zhen-yu, OUYANG Miao, XIAO Hong-bin, WANG Ju-shan, LI Tao, LIU Si-si   +5 more
doaj   +1 more source