Results 121 to 130 of about 4,881,979 (331)

LINE-1の発現は結腸直腸癌細胞におけるEGFR阻害剤の効果と関連している [PDF]

open access: yes, 2019
博士(医学) 甲第714号(主論文の要旨、要約、審査結果の要旨)博士(医学 ...
山本 英一郎
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Analisa Penyebab Cacat Pada Proses Produksi Galvanized Iron Divisi Coil to Coil (Shear Line 1 Dan 4) Di PT. Fumira Semarang [PDF]

open access: yes, 2006
Sebagai salah satu industri penghasil seng terbesar, PT Fumira selalu dituntut untuk meningkatkan kepuasan pelanggan antara lain dengan terus memperbaiki kualitas produk yang dihasilkan untuk dapat meminimasi biaya produksi dan meningkatkan output ...
Puspitasari, N. B. (Nia)
core  

Journal of Synchrotron Radiation welcomes seven new Co-editors

open access: yesJournal of Synchrotron Radiation
The newest seven members of the Editorial Board of Journal of Synchrotron Radiation are introduced.
Dibyendu Bhattacharyya   +2 more
doaj   +1 more source

Identification of charged amino acids required for nuclear localization of human L1 ORF1 protein

open access: yesMobile DNA, 2019
Background Long Interspersed Element 1 (LINE-1) is a retrotransposon that is present in 500,000 copies in the human genome. Along with Alu and SVA elements, these three retrotransposons account for more than a third of the human genome sequence.
B. T. Freeman   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Analisis Pengendalian Kualitas Menggunakan Diagram Kendali Demerit (Studi Kasus Produksi Air Minum Dalam Kemasan 240 Ml Di PT Tiw) [PDF]

open access: yes, 2014
The efforts to maintain and improve the quality of the resulting product with statistical process control. Demerit control chart is a control chart in which the defect type is categorized into several classes according to the level of disability ...
Ramadhani, G. S. (Gita)   +2 more
core  

The Use of Rhizospheric Microorganisms of Crotalaria for the Determination of Toxicity and Phytoremediation to Certain Petroleum Compounds

open access: yesPlants
Microbial toxicity tests in the rhizosphere play an important role in the risk assessment and phytoremediation of chemical compounds in the environment.
Ana Guadalupe Ramírez-May   +5 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

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