Results 101 to 110 of about 28,196,398 (315)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Assessing the Effect of Insulation Materials Used for Energy Conservation in Buildings on Indoor Radon—The Scale Model Room Approach

Applied Sciences
This study investigates how external insulation materials used for energy efficiency affect indoor radon accumulation, using a scale model room built with ignimbrite, a highly radon-emitting volcanic rock. Two insulation materials—mineral wool (open-cell,
Ilaria Rocchetti, Manuela Portaro, Paola Tuccimei, Gianfranco Galli, Michele Soligo, Cristina Longoni, Dino Vasquez   +6 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

The Field Monitoring and Numerical Simulation of Spatiotemporal Effects During Deep Excavation in Mucky Soft Soil: A Case Study

Applied Sciences
The issue of geotechnical hazards induced by excavation in soft soil areas has become increasingly prominent. However, the retaining structure and surface settlement deformation induced by the creep of soft soil and spatial effect of the excavation ...
Qiang Wu, Jianxiu Wang, Yanxia Long, Xuezeng Liu, Guanhong Long, Shuang Ding, Li Zhou, Huboqiang Li, Muhammad Akmal Hakim bin Hishammuddin   +8 more
doaj   +1 more source

Minnesota Tree Line: How to Buy a Tree, no.1, 1977

, 1977
This archival publication may not reflect current scientific knowledge or recommendations. Current information available from the University of Minnesota Extension: https://www.extension.umn.edu.University of Minnesota; McKinnon, Jane P..
University of Minnesota, McKinnon, Jane P.   +1 more
core  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Admiral Oriental Line Ma-Chiong instruction booklet, March 1, 1923

, 1923
1923The Admiral Line (also American Mail Line, and later Admiral Oriental Line) was a steamship company based in Seattle which operated five ocean liners sailing from Seattle to Japan and China.

core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

De cautione usufructuaria

quam ... pro summis in utroque iure honoribus ... doctoralibus rite impetrandis publicae censurae submittit Albertus à Line Bremensis, ad diem 17. Aprilis, anni M DC LXVNicht identisch mit VD17 7:639955P (dort: körperschaftl.
Line, Albert von
core   +1 more source