Results 81 to 90 of about 4,929,883 (200)

RNase H2, mutated in Aicardi-Goutières syndrome, promotes LINE-1 retrotransposition [PDF]

, 2018
Long INterspersed Element class 1 (LINE-1) elements are a type of abundant retrotransposons active in mammalian genomes. An average human genome contains ~100 retrotransposition-competent LINE-1s, whose activity is influenced by the combined action ...
Benitez-Guijarro, Maria, Cano, David, Fluteau, Adeline, Garcia-Cañadas, Marta, Garcia-Perez, Jose L., Heras, Sara R, Jackson, Andrew P., Kempen, Marie-Jeanne, Lopez-Ruiz, Cesar, Mohammad, Mahwish Mian, Murina, Olga, Reijns, Martin A. M., Sanchez, Laura, Sanchez-Pozo, Antonio, Tamauskaite, Zygimante, Vilar-Astasio, Raquel, Williams, Thomas C.   +16 more
core   +3 more sources

Expression of a large LINE-1-driven antisense RNA is linked to epigenetic silencing of the metastasis suppressor gene TFPI-2 in cancer [PDF]

LINE-1 retrotransposons are abundant repetitive elements of viral origin, which in normal cells are kept quiescent through epigenetic mechanisms.
Cruickshanks, H.A, Dunican, D.S., Lee, A., Lund, Jonathan N., Meehan, R.R., Sproul, D., Tufarelli, C., Vafadar-Isfahani, N.   +7 more
core   +1 more source

Data Systematization and Preliminary Analysis of Accidental Oil and Petroleum Product Spills in the Russian Arctic and Far North

Resources
The effects of climate change, such as melting ice and permafrost in northern and Arctic regions, raise serious concerns about the risk of accidents at oil production, transportation, and storage facilities.
Marina Nevskaya, Victor Belyaev, Sergey Aleshichev, Victoriya Vinogradova, Dinara Shagidulina   +4 more
doaj   +1 more source

Influence of Sand Content in Yili Loess on the Growth of Ecological Restoration Plants [PDF]

长江科学院院报
To investigate the effect of sand content on the growth of slope ecological restoration plants, we used the Analytic Hierarchy Process to select suitable plant species and then conducted planting experiment with sand added in Yili loess slopes.
YUAN Sheng-yang, YANG Gui-xia, LI Si-huan, CHU Jian-xun, YANG Xiao-ling, MA Jie, LIU Xian-feng
doaj   +1 more source

SIMBIO-VEG: an interdisciplinary project for improvement of organic systems and meth-ods in arable and vegetable cropping [PDF]

, 2006
SIMBIO-VEG is the first large interdisciplinary research project on organic farming ever being funded in Italy. The project partnership is composed of eight Working Units including Universities as well as public and private research centres and associa ...
Antichi, Daniele, Bigongiali, Federica, Bàrberi, Prof Dr Paolo, Mazzoncini, Prof Marco   +3 more
core  

The Scale Model Room Approach to Test the Performance of Airtight Membranes to Control Indoor Radon Levels and Radiation Exposure

Atmosphere
Indoor radon is one of the most significant contributors to lung cancer after smoking. Mitigation strategies based on protecting buildings with radon barrier materials, combined with home ventilation or room pressurization, are regularly used.
Manuela Portaro, Ilaria Rocchetti, Paola Tuccimei, Gianfranco Galli, Michele Soligo, Cristina Longoni, Dino Vasquez   +6 more
doaj   +1 more source

Circulating DNA markers in monitoring lung cancer: analysis of LINE-1 retroelement methylation status [PDF]

, 2018
It is known that the violation of DNA methylation processes is one of the earliest and most common events in malignant tumors. The purpose of this study was to perform a comparative analysis of the methylation level of LINE-1 retroelements in blood ...
Пономарева, А. А., Умарова, Л. А.   +1 more
core  

LINE-1 Based Insertional Mutagenesis Screens to Identify Genes Involved in Embryonic Stem Cell Differentiation

, 2016
Background: Knowledge of the intrinsic properties of embryonic stem cells is essential before the possibility of using these cells for therapeutic purposes becomes a reality. Insertional mutagenesis screens are widely used to identify genes sufficient to
Lee, Sung-Hun, Rangasamy, Danny
core   +1 more source

Assessing the Effect of Insulation Materials Used for Energy Conservation in Buildings on Indoor Radon—The Scale Model Room Approach

Applied Sciences
This study investigates how external insulation materials used for energy efficiency affect indoor radon accumulation, using a scale model room built with ignimbrite, a highly radon-emitting volcanic rock. Two insulation materials—mineral wool (open-cell,
Ilaria Rocchetti, Manuela Portaro, Paola Tuccimei, Gianfranco Galli, Michele Soligo, Cristina Longoni, Dino Vasquez   +6 more
doaj   +1 more source

The Field Monitoring and Numerical Simulation of Spatiotemporal Effects During Deep Excavation in Mucky Soft Soil: A Case Study

Applied Sciences
The issue of geotechnical hazards induced by excavation in soft soil areas has become increasingly prominent. However, the retaining structure and surface settlement deformation induced by the creep of soft soil and spatial effect of the excavation ...
Qiang Wu, Jianxiu Wang, Yanxia Long, Xuezeng Liu, Guanhong Long, Shuang Ding, Li Zhou, Huboqiang Li, Muhammad Akmal Hakim bin Hishammuddin   +8 more
doaj   +1 more source