Results 61 to 70 of about 28,196,398 (315)

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro   +11 more
wiley   +1 more source

[Central America] : father Neptune presenteth ye Grace Line fleet to ye olde Spanish Main

open access: yes, 2016
1 Mapa, color. - Mapa pictòric. - `... The informative interest of ths carte is historical and topograpical yet it is rendered in the manner humorous...`.
Grace Line [Companyia naviera]
core   +1 more source

FILTER-UNIT PULSE AND FLUCTUATING NOISE [PDF]

open access: yesVestnik KRAUNC: Fiziko-Matematičeskie Nauki, 2012
The technique and algorithms for identifying structural components of non-sinusoidal voltage and current signals in the ship power system. The skeleton diagram and useful model of active compensator conducted emissions on the basis of wavelet transform.
T.S. Goreva   +2 more
doaj   +1 more source

Precipitation Extremes and Their Synoptic Models in the Northwest European Sector of the Arctic during the Cold Season

open access: yesAtmosphere, 2022
Precipitation extrema over the Barents Sea and the neighbouring locations in Europe were analysed using data obtained from station observations and a highly detailed ERA5 re-analysis dataset.
Alexander Kislov   +2 more
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

LINE-1 and EPAS1 DNA methylation associations with high-altitude exposure

open access: yes, 2018
Recent discoveries indicate a genetic basis for high-altitude adaptation among human groups who have resided at high altitude for millennia, including Andeans, Tibetans, and Ethiopians.
Abigail W. Bigham (205218)   +8 more
core   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Reverberation Mapping and Implications for Narrow-Line Seyfert 1 Galaxies [PDF]

open access: yes, 2018
Reverberation mapping is the principal method for determining the masses of the central black holes that power AGNs. I will discuss recent reverberation mapping results in the context of how these affect our understanding of narrow-line Seyfert 1 ...
Dalla Bontà, Elena   +7 more
core   +1 more source

LINE-1 Cultured Cell Retrotransposition Assay [PDF]

open access: yes, 2016
The Long INterspersed Element-1 (LINE-1 or L1) retrotransposition assay has facilitated the discovery and characterization of active (i.e., retrotransposition-competent) LINE-1 sequences from mammalian genomes. In this assay, an engineered LINE-1 containing a retrotransposition reporter cassette is transiently transfected into a cultured cell line ...
Kopera, Huira C.   +5 more
openaire   +4 more sources

RNA sensor MDA5 suppresses LINE-1 retrotransposition by regulating the promoter activity of LINE-1 5′-UTR

open access: yesMobile DNA, 2021
Abstract Background Type 1 long interspersed elements, or LINE-1, are the only retroelements that replicate autonomously in human cells. The retrotransposition process of LINE-1 can trigger the activation of the innate immune system and has been proposed to play a role in the development of ...
Jiaxiu Yan   +8 more
openaire   +3 more sources

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