Results 131 to 140 of about 4,881,979 (331)

Aneuploidy in human embryonic cytotrophoblast with different level of global genome methylation [PDF]

, 2017
In this study, we investigated the frequency of aneuploidy of chromosomes 8 and X in human embryonic tissues with different level of global genome methylation.
Васильев, С. А., Савченко, Р. Р.   +1 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Development and Validation of a Machine Learning COVID-19 Veteran (COVet) Deterioration Risk Score

Critical Care Explorations
BACKGROUND AND OBJECTIVE:. To develop the COVid Veteran (COVet) score for clinical deterioration in Veterans hospitalized with COVID-19 and further validate this model in both Veteran and non-Veteran samples.
Sushant Govindan, MD, MSc, Alexandra Spicer, MS, Matthew Bearce, MPS, Richard S. Schaefer, PharmD, Andrea Uhl, BA, Gil Alterovitz, PhD, Michael J. Kim, MD, Kyle A. Carey, MPH, Nirav S. Shah, MD, MPH, Christopher Winslow, MD, Emily Gilbert, MD, Anne Stey, MD, MSc, Alan M. Weiss, MD, Devendra Amin, MD, George Karway, PhD, Jennie Martin, MS, Dana P. Edelson, MD, Matthew M. Churpek, MD, MPH, PhD   +17 more
doaj   +1 more source

Table S10 from Cancer Relevance of Circulating Antibodies Against LINE-1 Antigens in Humans

, 2023
Alexandra V. Vylegzhanina, Ivan A. Bespalov, Ksenia A. Novototskaya-Vlasova, Brandon M. Hall, Anatoli S. Gleiberman, Han Yu, Olga V. Leontieva, Katerina I. Leonova, Oleg V. Kurnasov, Andrei L. Osterman, Grace K. Dy, Alexey A. Komissarov, Elena Vasilieva, Jeff Gehlhausen, Akiko Iwasaki, Christine B. Ambrosone, Takemasa Tsuji, Junko Matsuzaki, Kunle Odunsi, Ekaterina L. Andrianova, Andrei V. Gudkov   +20 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Circulating DNA markers in monitoring lung cancer: analysis of LINE-1 retroelement methylation status [PDF]

, 2018
It is known that the violation of DNA methylation processes is one of the earliest and most common events in malignant tumors. The purpose of this study was to perform a comparative analysis of the methylation level of LINE-1 retroelements in blood ...
Пономарева, А. А., Умарова, Л. А.   +1 more
core  

Experimental investigation of productivity and surface integrity features in trim cut WEDM operation of hybrid metal matrix composite

International Journal of Lightweight Materials and Manufacture
Present study is focused on optimization of WEDM process parameters for increased productivity and improved surface quality of the machined surface of hybrid composite [Al6061 (90 %), SiC (2.5 %) and TiB2 (7.5 %)] by utilizing the trim cut strategy ...
Nilesh Kumar, Jatinder Kumar
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

CO2 absorption coefficients (ABSCO) tables for the 4700 to 5100 cm-1 region using Voigt profile accounting for the line-mixing

, 2020
Robab Hashemi
openalex   +1 more source

X-ray spectroscopy and time variability of Narrow Line Seyfert 1 [PDF]

, 2003
F. Cancelliere, A. Comastri
openalex   +1 more source