Results 131 to 140 of about 4,813,932 (329)

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

The Use of Rhizospheric Microorganisms of Crotalaria for the Determination of Toxicity and Phytoremediation to Certain Petroleum Compounds

Plants
Microbial toxicity tests in the rhizosphere play an important role in the risk assessment and phytoremediation of chemical compounds in the environment.
Ana Guadalupe Ramírez-May, María del Carmen Rivera-Cruz, María Remedios Mendoza-López, Rocío Guadalupe Acosta-Pech, Antonio Trujillo-Narcía, Consuelo Bautista-Muñoz   +5 more
doaj   +1 more source

X-ray spectroscopy and time variability of Narrow Line Seyfert 1 [PDF]

, 2003
F. Cancelliere, A. Comastri
openalex   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Development and Validation of a Machine Learning COVID-19 Veteran (COVet) Deterioration Risk Score

Critical Care Explorations
BACKGROUND AND OBJECTIVE:. To develop the COVid Veteran (COVet) score for clinical deterioration in Veterans hospitalized with COVID-19 and further validate this model in both Veteran and non-Veteran samples.
Sushant Govindan, MD, MSc, Alexandra Spicer, MS, Matthew Bearce, MPS, Richard S. Schaefer, PharmD, Andrea Uhl, BA, Gil Alterovitz, PhD, Michael J. Kim, MD, Kyle A. Carey, MPH, Nirav S. Shah, MD, MPH, Christopher Winslow, MD, Emily Gilbert, MD, Anne Stey, MD, MSc, Alan M. Weiss, MD, Devendra Amin, MD, George Karway, PhD, Jennie Martin, MS, Dana P. Edelson, MD, Matthew M. Churpek, MD, MPH, PhD   +17 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

On the Dirichlet to Neumann Problem for the 1-dimensional Cubic NLS equation on the Half-Line; Non-zero Initial Data [PDF]

, 2016
Dimitra C. Antonopoulou, Spyridon Kamvissis   +1 more
openalex   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Experimental investigation of productivity and surface integrity features in trim cut WEDM operation of hybrid metal matrix composite

International Journal of Lightweight Materials and Manufacture
Present study is focused on optimization of WEDM process parameters for increased productivity and improved surface quality of the machined surface of hybrid composite [Al6061 (90 %), SiC (2.5 %) and TiB2 (7.5 %)] by utilizing the trim cut strategy ...
Nilesh Kumar, Jatinder Kumar
doaj   +1 more source

LINE-1 activity and regulation in cancer

Frontiers in Bioscience, 2018
LINE-1 retrotransposons are ubiquitous genetic elements interspersed within the primary nuclear genome of modern day humans. Although shorter LINE-1-derived sequences occupy nearly one-in-five nucleotides of our genome, we are just beginning to appreciate the link between these important genetic elements and cancer, perhaps the most well-studied major ...
openaire   +2 more sources