Results 61 to 70 of about 4,813,932 (329)

Regulation of LINE-1 in mammals [PDF]

open access: yes, 2017
Transposable elements (TEs) are mobile DNA elements that represent almost half of the human genome. Transposition of TEs has been implicated as a source of genome evolution and acquisition of new traits but also as an origin of diseases.
Bodak, Maxime   +2 more
core  

Instability Mechanism of Cavity-Bearing Formation under Tunnel Excavation Disturbance

open access: yesAdvances in Civil Engineering, 2020
Urban subway construction inevitably causes disturbances to the rock strata. It can even cause ground collapse accidents when construction encounters a bad geological body in the stratum.
Tao Liu   +5 more
doaj   +1 more source

Context‐specific regulation of LINE‐1 [PDF]

open access: yesGenes to Cells, 2007
The present study was conducted to evaluate the contextual specificity of long interspersed nuclear element‐1 (LINE‐1 or L1) activation by cellular stress and the role of the aryl hydrocarbon receptor (AHR) transcription factor and oxidative stress in the gene activation response.
Ivo, Teneng   +2 more
openaire   +2 more sources

The MedSupport Multilevel Intervention to Enhance Support for Pediatric Medication Adherence: Development and Feasibility Testing

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction We developed MedSupport, a multilevel medication adherence intervention designed to address root barriers to medication adherence. This study sought to explore the feasibility and acceptability of the MedSupport intervention strategies to support a future full‐scale randomized controlled trial.
Elizabeth G. Bouchard   +8 more
wiley   +1 more source

Prediction of Ferromagnetic Ground State of NaCl-type FeN

open access: yes, 1998
Ab-initio results for structural and electronic properties of NaCl-type FeN are presented in a framework of plane-wave and ultrasoft pseudopotentials. Competition among different magnetic ordering is examined.
A. Filippetti   +13 more
core   +1 more source

Multi-functional BST2/tetherin against HIV-1, other viruses and LINE-1

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Bone marrow stromal cell antigen 2 (BST2), also known as CD317, HM1.24, or tetherin, is a type II transmembrane glycoprotein. Its expression is induced by IFN-I, and it initiates host immune responses by directly trapping enveloped HIV-1 particles onto ...
Yifei Zhao   +7 more
doaj   +1 more source

Unconventional translation of mammalian LINE-1 retrotransposons [PDF]

open access: yesGenes & Development, 2006
Long Interspersed Element-1 (LINE-1 or L1) retrotransposons encode proteins required for their mobility (ORF1p and ORF2p), yet little is known about how L1 mRNA is translated. Here, we show that ORF2 translation generally initiates from the first in-frame methionine codon of ORF2, and that both ORF1 and the inter-ORF spacer are dispensable for ORF2 ...
Reid S, Alisch   +4 more
openaire   +2 more sources

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis   +13 more
wiley   +1 more source

Methylation of retrotransposon Line-1 in atherosclerosis [PDF]

open access: yes, 2017
DNA methylation is one of the perspective but insufficiently studied epigenetic mechanisms which can be involved in atherosclerosis and related cardiovascular disease. Global DNA methylation estimated by the methylation level of retrotransposon LINE-1 in
Серебрякова, В. В.
core  

LINE-1 hypomethylation and HIST1H4F hypermethylation as oncomarkers in liquid biopsy of colorectal cancer

open access: yesУспехи молекулярной онкологии
Introduction. Local hypermethylation of gene promoters and global genome hypomethylation are well-known manifestations of aberrant methylation associated with carcinogenesis.
V. N. Kondratova   +4 more
doaj   +1 more source

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