Results 91 to 100 of about 9,613,096 (307)

Intra-line and inter-line genetic diversity in sire lines of the Old Kladruber horse based on microsatellite analysis of DNA

open access: yesCzech Journal of Animal Science, 2011
The Old Kladruber horse is the oldest original Czech horse breed - gene resource, with pedigree records spanning three centuries. Because the population is closed, there is a concern about the loss of genetic variation.
L. Vostrý   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Planar Minimum Curve Radius for Embedded Medium-low Speed Maglev Lines

open access: yesChengshi guidao jiaotong yanjiu
[Objective] As a new type of rail transit, the embedded medium-low speed maglev system relies on non-contact support for vehicle and track systems, and the vehicle running mechanism is embedded within the track beam. Therefore, it is crucial to study the
Mei JIANG, Junyu KOU, Yang WANG
doaj   +1 more source

Spring triticale yield and its stability depending on the genotype and environmental conditions

open access: yesPlant Varieties Studying and Protection, 2016
Purpose. Assessing stability of yield formation of complex-valued varieties and lines of spring triticale under conditions and of different years of their growing. Identifying the best genotypes for yield potential, plasticity and stability.
В. К. Рябчун   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

GRAPHO-ANALYTICAL STUDIES OF LINIAR EQUATION SYSTEMS

open access: yesJournal of Industrial Design and Engineering Graphics, 2016
The paper presents the solving of linear three variables system using two methods: analytic and graphic methods. The solving of a such system implies four cases: compatible system with unique solution, simple-indeterminate compatible system, double ...
Marin Dumitru, Ligia Petrescu
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Bayesian Estimates of Transmission Line Outage Rates That Consider Line Dependencies [PDF]

open access: yes, 2020
Transmission line outage rates are fundamental to power system reliability analysis. Line outages are infrequent, occurring only about once a year, so outage data are limited.
Wehenkel, Louis   +6 more
core  

Comparisons and Comments on Electron and Ion Impact Profiles of Spectral Lines

open access: yesOpen Astronomy, 2011
Stark broadening theory is currently operated for calculating widths and shifts of spectral lines that are needed for spectroscopic diagnostics and modeling in astrophysics, laboratory and technological plasmas. We have calculated a great number of data,
Sahal-Bréchot Sylvie   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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