Results 111 to 120 of about 17,013,485 (304)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Most Likely Separation of Intensity and Warping Effects in Image Registration
, 2017 This paper introduces a class of mixed-effects models for joint modeling of spatially correlated intensity variation and warping variation in 2D images. Spatially correlated intensity variation and warp variation are modeled as random effects, resulting ...
Kühnel, Line +3 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
LINE X TESTER ANALYSIS IN COMBINING ABILITIES ESTIMATION OF SUNFLOWER OIL CONTENT [PDF]
Poljoprivreda, 2012 Results of line x tester analysis for 15 sunflower genotypes of the Agricultural Institute Osijek are presented in this paper. Three A lines (cms) and three Rf testers with different oil content level (low, medium, high) in all combinations (nine ...
Ivica Liović +6 more
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Planar Minimum Curve Radius for Embedded Medium-low Speed Maglev Lines
Chengshi guidao jiaotong yanjiu[Objective] As a new type of rail transit, the embedded medium-low speed maglev system relies on non-contact support for vehicle and track systems, and the vehicle running mechanism is embedded within the track beam. Therefore, it is crucial to study the
Mei JIANG, Junyu KOU, Yang WANG
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Comparisons and Comments on Electron and Ion Impact Profiles of Spectral Lines
Open Astronomy, 2011 Stark broadening theory is currently operated for calculating widths and shifts of spectral lines that are needed for spectroscopic diagnostics and modeling in astrophysics, laboratory and technological plasmas. We have calculated a great number of data,
Sahal-Bréchot Sylvie +2 more
doaj +1 more source