Results 111 to 120 of about 9,613,096 (307)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The Effects of Praise-seeking Need and Rejection-avoidance Need on Friendship Formation and Maintenance in LINE [PDF]
, 2016 メッセンジャ型のスマートフォン用アプリケーションであるLINEは2011年のサービス開始以降、日本国内では10～20代の年齢層を中心に急速に利用者数を増加させている（総務省, 2015）。本研究では大学生を対象にLINEでのコミュニケーションにおける承認欲求（賞賛獲得欲求・拒否回避欲求）の影響力を検討した。新たに友人関係を築こうとする際に相手とLINEのアカウントを交換するタイミングや、関係を解消したいと考えている相手からLINEのメッセージが送られてきた場合の対処について ...
KOJIMA, Yayoi +3 more
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
, 1900 Black and white structural drawing for Oregon Short Line Railroad ...
Oregon Short Line Railroad
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Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
American Romanticism, Poe and “The Rationale of Verse”
American and British Studies Annual, 2016 Although “The Philosophy of Composition” is usually referred to as Edgar Allan Poe’s best-known critical essay,“The Rationale of Verse” can certainly be seen as his most elaborate.
Saša Simović, Marija Mijušković
doaj
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
, 1917 V. Ut. 2. S. L. 2c; Sheet No. S. L. 2c of Val. Sec. Ut. 2 of Oregon Short Line Railroad Gravel Pits and survey station 1818 + 25.0 to survey station 1823 + 95.0 Main Line; Salt Lake County Main Line Map No ...
Oregon Short Line Railroad
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