Results 121 to 130 of about 5,133,076 (269)

Cash Transfers in the Perinatal Period and Investigations of Infant Maltreatment. [PDF]

open access: yesJAMA Pediatr
Agarwal S   +5 more
europepmc   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Drawings, lines and lines

open access: yes, 2012
Este artigo conta a história de Caio, um aluno com espectro autista, matriculado em escola comum, descrevendo seu percurso dos cinco aos oito anos. O objetivo é compartilhar as dúvidas, os acertos e as flexibilizações que foram sendo realizados para que Caio usufruísse do dia a dia escolar, tendo sua singularidade respeitada, criando a possibilidade de
Affonso, Gláucia   +1 more
openaire   +1 more source

The micro-phenomenology of Floatation-REST. [PDF]

open access: yesBMC Complement Med Ther
Hruby H   +3 more
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

The use of cladribine tablets in patients with MS beyond the age of 50: experiences from a large tertiary German centre. [PDF]

open access: yesNeurol Res Pract
Axhausen F   +6 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Virulence determinants and toxin profile of methicillin resistant Staphylococcus aureus from commercial cheese in Bangladesh: A public health risk. [PDF]

open access: yesPLoS One
Hossain MT   +10 more
europepmc   +1 more source

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