Results 71 to 80 of about 1,174,395 (311)
The dynamic contact angle, the angle between the surfaces of the liquid and the solid at a moving contact line, is one of the primary conditions for the dynamics of the liquid surface confined by solid wall.
Takahiro ITO +6 more
doaj +1 more source
Multiscale Mixed Hydrodynamics in Line Contacts [PDF]
Abstract In the hydrodynamic line contact, there is a very thin layer physically adsorbed to the solid surface. When the surface separation is sufficiently small, the Hertzian contact zone will be completely filled with the boundary layer, while in most of the inlet zone still occurs continuum hydrodynamics, which lies between the mated ...
openaire +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Phenomenological contact line friction coefficient
An important feature of contact line motion, as an irreversible process, is its dissipative nature, which can dominate the dynamics during the early stages of droplet spreading.
Jiaxing Shen +2 more
doaj +1 more source
Contact Stress Analysis of Traction Drives of a New Type Bearing Reducer
An arc is constructed at the end of the planetary wheel profile shaft of the planetary traction drive, and the contact point between the arc and the outer ring and the end face of the solar wheel shaft is kept on the radial traction contact line.
Shu Hongyu, Zhao Liang, Yu Yijie
doaj
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Contact Angle Measurements of the Apparent Line Tension Are Spurious
Phenomena in diverse contexts such as wetting, biological assembly, and manufacturing are attributed to the three-phase line tension. However, decades of line tension estimates based on contact angles of droplets controversially span 6 orders of ...
An, Hongjie, Tan, Beng Hau
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source

