Results 71 to 80 of about 1,174,395 (311)

Experimental investigation on the effect of accelerating motion of contact line on the dynamic contact angle

open access: yesNihon Kikai Gakkai ronbunshu, 2014
The dynamic contact angle, the angle between the surfaces of the liquid and the solid at a moving contact line, is one of the primary conditions for the dynamics of the liquid surface confined by solid wall.
Takahiro ITO   +6 more
doaj   +1 more source

Multiscale Mixed Hydrodynamics in Line Contacts [PDF]

open access: yesContinuum Mechanics and Thermodynamics, 2021
Abstract In the hydrodynamic line contact, there is a very thin layer physically adsorbed to the solid surface. When the surface separation is sufficiently small, the Hertzian contact zone will be completely filled with the boundary layer, while in most of the inlet zone still occurs continuum hydrodynamics, which lies between the mated ...
openaire   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Phenomenological contact line friction coefficient

open access: yesDroplet
An important feature of contact line motion, as an irreversible process, is its dissipative nature, which can dominate the dynamics during the early stages of droplet spreading.
Jiaxing Shen   +2 more
doaj   +1 more source

Contact Stress Analysis of Traction Drives of a New Type Bearing Reducer

open access: yesJixie chuandong, 2023
An arc is constructed at the end of the planetary wheel profile shaft of the planetary traction drive, and the contact point between the arc and the outer ring and the end face of the solar wheel shaft is kept on the radial traction contact line.
Shu Hongyu, Zhao Liang, Yu Yijie
doaj  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Contact Angle Measurements of the Apparent Line Tension Are Spurious

open access: yes
Phenomena in diverse contexts such as wetting, biological assembly, and manufacturing are attributed to the three-phase line tension. However, decades of line tension estimates based on contact angles of droplets controversially span 6 orders of ...
An, Hongjie, Tan, Beng Hau
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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