Results 91 to 100 of about 1,124,322 (266)
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Jixie chuandong, 2013 The accurate formula of helical gear’s contact line length is derived,and then its changing law and dynamic statistical law of meshing process are analyzed,the dynamic stat istical law of the contact line length change curve are obtained and simulated ...
叶友东, 周哲波
doaj
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Study of instantaneous starvation at a finite-length line contact [PDF]
Jurnal Tribologi, 2019 Starvation phenomenon widely exists in the non-conforming contacts when high-viscosity lubricating oil or greases are used. However, most of the work focuses on the steady state starvation, and the phenomenon of instantaneous starvation is not well ...
Xuejin Shen +3 more
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Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Nauka ta progres transportu, 2010 The article is dealt with the selecting methodology of overvoltage arresters for DC traction line.
Ye. D. Kim, V. H. Sychenko
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Analysis of Dynamic Wetting and Dewetting on a Hydrophobic Surface Using Molecular Kinetic Theory
Tribology OnlineThe dynamic wetting and dewetting of a water droplet on a hydrophobic solid surface with an equilibrium contact angle of approximately 100° was investigated using molecular kinetic (MK) theory to model the extension–contraction experiment and numerically
Chinatsu Saito +3 more
doaj +1 more source