Results 81 to 90 of about 1,174,395 (311)
BuildingsLarge-span structures may experience progressive collapse involving complex member collisions, for which efficient and accurate simulation remains a challenging problem in engineering practice.
Qiang Xu +4 more
doaj +1 more source
Volume and Frequency-Independent Spreading of Droplets Driven by Ultrasonic Surface Vibration
Fluids, 2020 Many industrial processes depend on the wetting of liquids on various surfaces. Understanding the wetting effects due to ultrasonic vibration could provide a means for changing the behavior of liquids on any surface.
Matthew Trapuzzano +3 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
An asperity-based finite element model for electrical contact of microswitches [PDF]
, 2013 Precise prediction of electrical contact resistance is important for microswitches. The contact spot used to beconsidered as a circle in earlier literature, where there was only one geometrical parameter: the radius of the a-spots.
Colin, Stephane +7 more
core +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
An explicit solution to a three-dimensional wedge problem considering two edges effect
Friction, 2019 The paper presents an explicit matrix algorithm to solve the problem of an elastic wedge with three loaded surfaces. The algorithm makes use of a recently published concept of transformation matrix, by which the original surface loads are converted to ...
L. Guo +4 more
doaj +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
CONTACT AND ROTATION ANALYSIS OF SINGLE ROLLER ENVELOPING FACE WORM DRIVE
Jixie qiangdu, 2021 Based on the meshing theory of single roller enveloping end face worm drive,the distribution of contact line and the length of contact line on the cylindrical surface of the drive pair,and the self-rotation angle of the roller,and the self-rotation angle
LIAO HongHui +3 more
doaj
Numerical simulation of interdigitated back contact hetero-junction solar cells [PDF]
, 2013 The goal of this thesis is the application of an opto-electronic numerical simulation to heterojunction silicon solar cells featuring an all back contact architecture (Interdigitated Back Contact Hetero-Junction IBC-HJ).
Callozzo, Alessandro
core