Results 241 to 250 of about 5,298,176 (299)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Radioresistant intrathymic stem cells: retrospective analysis and concept of the role in thymic oncogenesis and post-irradiation regeneration. [PDF]

Front Immunol
Shichkin VP.
europepmc   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Enhanced projectile path estimation using multi-vehicle FMCW radar sensors. [PDF]

Sci Rep
Salama AA, Hussein MA.
europepmc   +1 more source

Emission-Programmed Femtosecond Bessel Beams for Fabricating Micro-Nano Hierarchical Structures. [PDF]

Nanomaterials (Basel)
Lu Y, Kai L, Yin F, Yang Q, Yue K, Chen F.   +5 more
europepmc   +1 more source

Carboxyl-Terminal Region of the Maturation Protein of RNA Coliphage Qβ Mediates Host Attachment, Virion Formation, and Cell Lysis. [PDF]

Genes Cells
Kajitani M, Hakoshima N, Inokuchi Y.
europepmc   +1 more source

CD13 activation assembles phosphoinositide (PI) signaling complexes to regulate the actin cytoskeleton. [PDF]

Sci Rep
Meredith E, Aguilera B, Sharma R, Thimma N, McGurk F, Zong P, Yue L, Shapiro LH, Ghosh M.   +8 more
europepmc   +1 more source

Permittivity extraction of sandy soils through uncalibrated and thickness-independent meniscus-free measurements using a hollow coaxial line. [PDF]

Sci Rep
Hasar UC, Korkmaz H, Kaya Y.
europepmc   +1 more source

CRISPR-engineered human lung organoids with a biomolecular condensate reporter enable mechanistic toxicity monitoring. [PDF]

Mater Today Bio
Kim SY, Baek JW, Kim EJ, Srinivasan S, Kim KK, Kim EM.   +5 more
europepmc   +1 more source