Results 31 to 40 of about 252,055 (264)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

On the continuity of Weil-Petersson volumes of the moduli space weighted points on the projective line

open access: yesComplex Manifolds, 2022
In this work we show that the Weil-Petersson volume (which coincides with the CM degree) in the case of weighted points in the projective line is continuous when approaching the Calabi-Yau geometry from the Fano geometry. More specifically, the CM volume
Tambasco Salvatore
doaj   +1 more source

Physics-based surge point identification for unsupervised CFD-computation of centrifugal compressor speed lines

open access: yesEnergy Conversion and Management: X, 2023
We present a speed line calculation model using physics-based surge point identification. When using surrogate model-based design of experiment (DOE) techniques, the large number of computations demands an automated, unsupervised process to calculate the
Yannick Lattner   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Correspondences between convex geometry and complex geometry [PDF]

open access: yesÉpijournal de Géométrie Algébrique, 2017
We present several analogies between convex geometry and the theory of holomorphic line bundles on smooth projective varieties or K\"ahler manifolds. We study the relation between positive products and mixed volumes.
Brian Lehmann, Jian Xiao
doaj   +1 more source

Comparison of Single-Site Ionospheric Delays Derived from Geometry-Free and Geometry-Based Approaches with an Analysis of Orbit and Clock Error Effects

open access: yesAtmosphere, 2021
The reparameterization of the geometry-free and geometry-based approaches to derive single-site ionospheric delays using Global Navigation Satellite System (GNSS) measurements is described.
Sijing Liu   +4 more
doaj   +1 more source

Absolute Embeddings of Point–Line Geometries

open access: yesJournal of Algebra, 2001
The paper concerns the existence of absolute embeddings \(e\) of point-line geometries \(\Gamma=({\mathcal P},{\mathcal L})\), that is, any embedding of \(\Gamma\) in some projective space can be derived from \(e\) by projecting onto suitable quotient spaces.
Kasikova, A, Shult, E
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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