Results 61 to 70 of about 1,522,870 (339)

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

Pattern Formation and Tropical Geometry

open access: yesFrontiers in Physics, 2020
Sandpile models exhibit fascinating pattern structures: patches, characterized by quadratic functions, and line-shaped patterns (also called solitons, webs, or linear defects).
Nikita Kalinin, Nikita Kalinin
doaj   +1 more source

On the continuity of Weil-Petersson volumes of the moduli space weighted points on the projective line

open access: yesComplex Manifolds, 2022
In this work we show that the Weil-Petersson volume (which coincides with the CM degree) in the case of weighted points in the projective line is continuous when approaching the Calabi-Yau geometry from the Fano geometry. More specifically, the CM volume
Tambasco Salvatore
doaj   +1 more source

Comparison of Single-Site Ionospheric Delays Derived from Geometry-Free and Geometry-Based Approaches with an Analysis of Orbit and Clock Error Effects

open access: yesAtmosphere, 2021
The reparameterization of the geometry-free and geometry-based approaches to derive single-site ionospheric delays using Global Navigation Satellite System (GNSS) measurements is described.
Sijing Liu   +4 more
doaj   +1 more source

One dimensional metrical geometry [PDF]

open access: yes, 2007
One dimensional metrical geometry may be developed in either an affine or projective setting over a general field using only algebraic ideas and quadratic forms.
Wildberger, N J
core   +2 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Correspondences between convex geometry and complex geometry [PDF]

open access: yesÉpijournal de Géométrie Algébrique, 2017
We present several analogies between convex geometry and the theory of holomorphic line bundles on smooth projective varieties or K\"ahler manifolds. We study the relation between positive products and mixed volumes.
Brian Lehmann, Jian Xiao
doaj   +1 more source

A polar+equatorial wind model for broad absorption line quasars: I. Fitting the C IV BAL profiles

open access: yes, 2010
Despite all the studies, the geometry of the wind at the origin of the blueshifted broad absorption lines (BAL) observed in nearly 20% of quasars still remains a matter of debate.
Arav   +82 more
core   +1 more source

Geometry of straight lines pencils

open access: yesFacta universitatis - series: Architecture and Civil Engineering, 2002
This paper considers a pencil of straight Unes in the Euclidean plane as well as the same pencil of straight lines in the projective plane where the projective geometry model M" is defined with its points forming the sets of (n-l) collinear points, whose supporting straight lines belong to the considered pencil of straight lines.
Milan Janic, Dejan Tanikic
openaire   +4 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

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