Results 151 to 160 of about 5,172,585 (353)
A novel algebraic technique for adjacency matrices of some derived graphs
Mathematical and Computer Modelling of Dynamical SystemsGraph energy has been the main concern of spectral graph theory in the last five decades. The classical graph energy is the sum of the absolute values of the eigenvalues of the adjacency matrix. In many research papers, different versions of graph energy
Hacer Ozden Ayna +5 more
doaj +1 more source
Extension of Space Syntax Methods to Generic Urban Variables
Urban Science, 2018 We studied generalization of a method for extending configurational studies to variables that are not exclusively geographical, in order to allow investigation of generic relationships in the built environment.
Roberto D’Autilia, Marco Spada
doaj +1 more source
The asymptotic behavior of some indices of iterated line graphs of regular graphs
, 2012 In this paper, we consider the asymptotic behavior of the number of spanning trees and the Kirchhoff index of iterated line graphs and iterated para-line graphs (or clique-inserted graphs) of a regular graph G.
Yan, Weigen +3 more
core
On the Line Degree Splitting Graph of a Graph
, 2017 In this paper, we introduce the concept of the line degree splitting graph of a graph. We obtain some properties of this graph. We find the girth of the line degree splitting graphs.
B. Basavanagoud, Roopa S. Kusugal
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Adaptive feature thresholding for off-line signature verification
, 2008 This paper introduces Adaptive Feature Thresholding (AFT) which is a novel method of person-dependent off-line signature verification. AFT enhances how a simple image feature of a signature is converted to a binary feature vector by significantly ...
Larkins, Robert L. +3 more
core +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Decomposing Berge graphs and detecting balanced skew partitions [PDF]
We prove that the problem of deciding whether a graph has a balanced skew partition is NP-hard. We give an O(n9)-time algorithm for the same problem restricted to Berge graphs.
Nicolas Trotignon
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source