Results 51 to 60 of about 168,150,866 (290)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Geometric characteristics of quantum evolution: curvature and torsion
Condensed Matter Physics, 2017 We study characteristics of quantum evolution which can be called curvature and torsion. The curvature shows a deviation of the state vector in quantum evolution from the geodesic line.
H.P. Laba, V.M. Tkachuk
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
The Astrophysical Journal LettersWe employ first-principles, fully kinetic particle-in-cell simulations to investigate magnetic field-line curvature in magnetically dominated turbulent plasmas and its role in particle acceleration through curvature-drift motion along the motional ...
Samuel T. Sebastian, Luca Comisso
doaj +1 more source
i-Perception, 2017 We report a novel illusion––curvature blindness illusion: a wavy line is perceived as a zigzag line. The following are required for this illusion to occur.
Kohske Takahashi
doaj +1 more source
The curvature of the QCD crossover line [PDF]
Proceedings of The 36th Annual International Symposium on Lattice Field Theory — PoS(LATTICE2018), 2019 We map out the QCD crossover line $\frac{T_c(\mu_B)}{T_c(0)} = 1 - \kappa_2 \left(\frac{\mu_B}{T_c(0)} \right)^2 - \kappa_4 \left( \frac{\mu_B}{T_c(0)} \right)^4 + \mathcal{O}(\mu_B^6)$ for the first time up to $\mathcal{O}(\mu_B^4)$ for a strangeness neutral system by performing a Taylor expansion of chiral observables in temperature $T$ and chemical ...
openaire +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Robust and Accurate Curvature Estimation Using Adaptive Line Integrals
EURASIP Journal on Advances in Signal Processing, 2010 The task of curvature estimation from discrete sampling points along a curve is investigated. A novel curvature estimation algorithm based on performing line integrals over an adaptive data window is proposed.
Chiu Yen-Lin +4 more
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